{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T14:23:11Z","timestamp":1793110991730,"version":"4.5.0"},"reference-count":24,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T00:00:00Z","timestamp":1769558400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T00:00:00Z","timestamp":1769558400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Women's Health"],"published-print":{"date-parts":[[2026,3,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background and Objective:<\/jats:title>\n                    <jats:p>Preeclampsia (PE), a hypertensive disorder of pregnancy, is a leading cause of maternal morbidity and mortality globally. Low-dose aspirin (LDA) is recommended for PE prevention in high- and moderate-risk women. Despite clinical trial evidence, adherence to LDA guidelines and disparities in usage remain underexplored in real-world settings. This study assesses LDA initiation rates among high- and moderate-risk pregnant women, examining disparities by race, geography, and hospital characteristics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We conducted a retrospective cross-sectional analysis of the U.S. Nationwide Inpatient Sample (2016\u20132021). Pregnancy-associated hospitalizations were identified using International classification disease-10 (ICD-10) codes, and PE risk factors were classified as high or moderate based on the United States Preventive Services Task Force and American College of Obstetricians and Gynecologists criteria. Statistical analyses included descriptive statistics, bivariate analyses, and joinpoint regression to evaluate temporal trends and disparities in LDA use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Among 23,163,717 hospitalizations, 8.2% were high-risk and 13.3% moderate-risk for PE. LDA use increased across all groups from 2016 to 2021, but remained lower among moderate-risk women. Racial disparities were evident, with Black and Hispanic women in the moderate-risk group demonstrating lower LDA utilization compared with White women. Geographic disparities revealed the Midwest and Northeast leading in LDA use, whereas rural hospitals consistently reported the lowest rates. Urban teaching hospitals had higher LDA use compared with rural and nonteaching hospitals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>LDA use for PE prevention has improved, but significant disparities persist by race, region, and hospital type. Provider education, capacity-building in underserved areas, and enhanced documentation are essential to ensure equitable access to this evidence-based intervention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15409996251405065","type":"journal-article","created":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T07:40:21Z","timestamp":1766994021000},"page":"290-298","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Trends and Disparities in the Utilization of Low-Dose Aspirin for Pregnancies with Moderate or High-Risk of Preeclampsia: A National Study"],"prefix":"10.1177","volume":"35","author":[{"given":"Mulubrhan F.","family":"Mogos","sequence":"first","affiliation":[{"name":"Center for Research Development and Scholarship, School of Nursing, Vanderbilt University, Nashville, Tennessee, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Adkins","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhruvi","family":"Parmar","sequence":"additional","affiliation":[{"name":"Center for Research Development and Scholarship, School of Nursing, Vanderbilt University, Nashville, Tennessee, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadie B.","family":"Sommer","sequence":"additional","affiliation":[{"name":"Center for Research Development and Scholarship, School of Nursing, Vanderbilt University, Nashville, Tennessee, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taneisha R.","family":"Gillyard","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, Meharry Medical College, Nashville, Tennessee, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etoi A.","family":"Garrison","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,1,28]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.14781"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2021.09.008"},{"key":"e_1_3_3_4_2","unstructured":"Hypertension in pregnancy: diagnosis and management. London: National Institute for Health and Care Excellence (NICE); 2019 Jun 25. (NICE Guideline No. 133). Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK546004\/"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/aog.0000000000002709"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2021.01.032"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2018.5972"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.20859"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.936560"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-021-06349-4"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2018.33.e213"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-023-01842-3"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/aog.0000000000004363"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.2021.01466"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare11030438"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-022-07995-3"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/adm.0000000000000979"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/aog.0000000000005678"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.7326\/m19-3254"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.44121"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1101\/2024.05.20.24307230"},{"key":"e_1_3_3_22_2","volume-title":"Health Policy Center ib, Robert Wood Johnson Foundation ib. Advancing maternal health equity in southern states: what are Medicaid programs doing and what more could they do?","author":"Haley JM","year":"2022","unstructured":"Haley JM, , Hinojosa S, , Lacy L, et al. Health Policy Center ib, Robert Wood Johnson Foundation ib. Advancing maternal health equity in southern states: what are Medicaid programs doing and what more could they do?. 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