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In situ hydridization demonstrated expression of MMP-8 in osteoblasts, osteocytes, periodontal ligament cells, cementoblasts, and cementocytes along with collagen types I and III. In contrast, transcripts of MMP-13 were confined to a small population of osteoblasts and osteocytes in alveolar bone. The results suggested that MMP-8 may be involved in remodeling the periodontium during tooth eruption, and its expression may be coordinated with that of collagen types I and III, whereas the participation of MMP-13 may be rather limited.<\/jats:p>","DOI":"10.1177\/154405910208101004","type":"journal-article","created":{"date-parts":[[2009,1,8]],"date-time":"2009-01-08T19:39:42Z","timestamp":1231443582000},"page":"673-678","source":"Crossref","is-referenced-by-count":50,"title":["Expression of MMP-8 and MMP-13 mRNAs in Rat Periodontium during Tooth                Eruption"],"prefix":"10.1177","volume":"81","author":[{"given":"M.","family":"Tsubota","sequence":"first","affiliation":[{"name":"Division of Periodontics and Endodontics, Tohoku University Graduate\r               School of Dentistry, Sendai 980-8575, Japan;"},{"name":"Division of Oral Molecular Biology, Tohoku University Graduate School\r               of Dentistry, Sendai 980-8575, Japan; and"},{"name":"Division of Orthodontics, Tohoku University Graduate School of\r               Dentistry, Sendai 980-8575, Japan;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Sasano","sequence":"additional","affiliation":[{"name":"Division of Periodontics and Endodontics, Tohoku University Graduate\r               School of Dentistry, Sendai 980-8575, Japan;"},{"name":"Division of Oral Molecular Biology, Tohoku University Graduate School\r               of Dentistry, Sendai 980-8575, Japan; and"},{"name":"Division of Orthodontics, Tohoku University Graduate School of\r               Dentistry, Sendai 980-8575, Japan;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Division of Periodontics and Endodontics, Tohoku University Graduate\r               School of Dentistry, Sendai 980-8575, Japan;"},{"name":"Division of Oral Molecular Biology, Tohoku University Graduate School\r               of Dentistry, Sendai 980-8575, Japan; and"},{"name":"Division of Orthodontics, Tohoku University Graduate School of\r               Dentistry, Sendai 980-8575, Japan;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Kagayama","sequence":"additional","affiliation":[{"name":"Division of Periodontics and Endodontics, Tohoku University Graduate\r               School of Dentistry, Sendai 980-8575, Japan;"},{"name":"Division of Oral Molecular Biology, Tohoku University Graduate School\r               of Dentistry, Sendai 980-8575, Japan; and"},{"name":"Division of Orthodontics, Tohoku University Graduate School of\r               Dentistry, Sendai 980-8575, Japan;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Shimauchi","sequence":"additional","affiliation":[{"name":"Division of Periodontics and Endodontics, Tohoku University Graduate\r               School of Dentistry, Sendai 980-8575, Japan;"},{"name":"Division of Oral Molecular Biology, Tohoku University Graduate School\r               of Dentistry, Sendai 980-8575, Japan; and"},{"name":"Division of Orthodontics, Tohoku University Graduate School of\r               Dentistry, Sendai 980-8575, Japan;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2002,10,1]]},"reference":[{"key":"BALBIN-ETAL-2001","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M007674200"},{"key":"BIRKEDAL-HANSEN-ETAL-1993","doi-asserted-by":"publisher","DOI":"10.1177\/10454411930040020401"},{"key":"BOLCATO-BELLEMIN-ETAL-2000","doi-asserted-by":"publisher","DOI":"10.1177\/00220345000790091201"},{"key":"CAWSTON-1998","unstructured":"Cawston TE -1998- Interstitial collagenase. 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