{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T04:29:05Z","timestamp":1784867345256,"version":"3.55.0"},"reference-count":18,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2003,7,1]],"date-time":"2003-07-01T00:00:00Z","timestamp":1057017600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[2003,7]]},"abstract":"<jats:p>\n                    We previously reported that, before tooth eruption, over one-half of infants aged 6 mos were already infected with Streptococcus mutans. The aim of this investigation was to determine the colonization of S. mutans after tooth eruption in the same cohort of 111 infants (35 pre-term, 76 full-term). Our results showed that S. mutans colonization increased with increasing age, so that by 24 mos of age, 84% harbored the bacteria (p &lt; 0.01). The mean and median ages of S. mutans colonization in dentate infants were 15.7 mos and 16.0 mos, respectively. Factors associated with S. mutans colonization were sweetened fluids taken to bed (p &lt; 0.01), frequent sugar exposure (p &lt; 0.03) and snacking (p &lt; 0.03), sharing of foods with adults (p &lt; 0.03), and maternal S. mutans levels of &gt; 10\n                    <jats:sup>5<\/jats:sup>\n                    CFU\/mL (p &lt; 0.02). In contrast, non-colonization of S. mutans was associated with toothbrushing (p &lt; 0.03) and multiple courses of antibiotics (p &lt; 0.001). Analysis of our data establishes the timing of S. mutans colonization in children from birth to 24 mos of age.\n                  <\/jats:p>","DOI":"10.1177\/154405910308200703","type":"journal-article","created":{"date-parts":[[2009,1,8]],"date-time":"2009-01-08T19:39:42Z","timestamp":1231443582000},"page":"504-508","source":"Crossref","is-referenced-by-count":111,"title":["A Longitudinal Study of\n                    <i>Streptococcus mutans<\/i>\n                    Colonization in Infants after Tooth Eruption"],"prefix":"10.1177","volume":"82","author":[{"given":"A.K.L.","family":"Wan","sequence":"first","affiliation":[{"name":"University of Queensland, School of Dentistry, 200 Turbot Street, Brisbane, Queensland 4000, Australia;"},{"name":"Queensland Institute of Medical Research, Population & Clinical Sciences Division, Herston Rd., Brisbane, Queensland 4006, Australia;"},{"name":"Oral Biology Laboratory, University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia; and"},{"name":"Mater Misericordiae Hospitals, Raymond Tce., South Brisbane, Queensland 4105, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.K.","family":"Seow","sequence":"additional","affiliation":[{"name":"University of Queensland, School of Dentistry, 200 Turbot Street, Brisbane, Queensland 4000, Australia;"},{"name":"Queensland Institute of Medical Research, Population & Clinical Sciences Division, Herston Rd., Brisbane, Queensland 4006, Australia;"},{"name":"Oral Biology Laboratory, University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia; and"},{"name":"Mater Misericordiae Hospitals, Raymond Tce., South Brisbane, Queensland 4105, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.M.","family":"Purdie","sequence":"additional","affiliation":[{"name":"University of Queensland, School of Dentistry, 200 Turbot Street, Brisbane, Queensland 4000, Australia;"},{"name":"Queensland Institute of Medical Research, Population & Clinical Sciences Division, Herston Rd., Brisbane, Queensland 4006, Australia;"},{"name":"Oral Biology Laboratory, University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia; and"},{"name":"Mater Misericordiae Hospitals, Raymond Tce., South Brisbane, Queensland 4105, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.S.","family":"Bird","sequence":"additional","affiliation":[{"name":"University of Queensland, School of Dentistry, 200 Turbot Street, Brisbane, Queensland 4000, Australia;"},{"name":"Queensland Institute of Medical Research, Population & Clinical Sciences Division, Herston Rd., Brisbane, Queensland 4006, Australia;"},{"name":"Oral Biology Laboratory, University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia; and"},{"name":"Mater Misericordiae Hospitals, Raymond Tce., South Brisbane, Queensland 4105, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.J.","family":"Walsh","sequence":"additional","affiliation":[{"name":"University of Queensland, School of Dentistry, 200 Turbot Street, Brisbane, Queensland 4000, Australia;"},{"name":"Queensland Institute of Medical Research, Population & Clinical Sciences Division, Herston Rd., Brisbane, Queensland 4006, Australia;"},{"name":"Oral Biology Laboratory, University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia; and"},{"name":"Mater Misericordiae Hospitals, Raymond Tce., South Brisbane, Queensland 4105, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.I.","family":"Tudehope","sequence":"additional","affiliation":[{"name":"University of Queensland, School of Dentistry, 200 Turbot Street, Brisbane, Queensland 4000, Australia;"},{"name":"Queensland Institute of Medical Research, Population & Clinical Sciences Division, Herston Rd., Brisbane, Queensland 4006, Australia;"},{"name":"Oral Biology Laboratory, University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia; and"},{"name":"Mater Misericordiae Hospitals, Raymond Tce., South Brisbane, Queensland 4105, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2003,7,1]]},"reference":[{"key":"CAUFIELD-ETAL-1993","doi-asserted-by":"publisher","DOI":"10.1177\/00220345930720010501"},{"key":"HABIBIAN-ETAL-2002","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9969(02)00017-1"},{"key":"KARN-ETAL-1998","doi-asserted-by":"publisher","DOI":"10.1111\/j.1752-7325.1998.tb03001.x"},{"key":"KOHLER-AND-BRATTHALL-1978","doi-asserted-by":"crossref","unstructured":"Kohler B, Bratthall D -1978- Intrafamilial levels of\n                      Streptococcus mutans\n                      and some aspects of the bacterial transmission. Scand J Dent Res 86:35\u201342.","DOI":"10.1111\/j.1600-0722.1978.tb00605.x"},{"key":"KOHLER-ETAL-1988","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1988.tb00598.x"},{"key":"LAI-ETAL-1997","unstructured":"Lai PY, Seow WK, Tudehope DI, Rogers YI -1997- Enamel hypoplasia and dental caries in very-low birthweight children: a case-controlled longitudinal study. Pediatr Dent 19:42\u201349."},{"key":"LI-AND-CAUFIELD-1995","doi-asserted-by":"publisher","DOI":"10.1177\/00220345950740020901"},{"key":"LI-ETAL-1994","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(94)90058-2"},{"key":"LOESCHE-1986","doi-asserted-by":"publisher","DOI":"10.1128\/mr.50.4.353-380.1986"},{"key":"MASUDA-ETAL-1979","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.10.4.497-502.1979"},{"key":"PASCOE-AND-SEOW-1994","unstructured":"Pascoe L, Seow WK -1994- Enamel hypoplasia and dental caries in Australian aboriginal children: prevalence and correlation between the two diseases. Pediatr Dent 16:193\u2013199."},{"key":"SAUVE-AND-GEGGIE-1991","unstructured":"Sauve RS, Geggie JH -1991- Growth and dietary status of preterm and term infants during the first two years of life. Can J Public Health 82:95\u2013100."},{"key":"SEOW-1998","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.1998.tb02090.x"},{"key":"SEOW-ETAL-1987","unstructured":"Seow WK, Humphrys C, Tudehope DI -1987- Increased prevalence of developmental dental defects in low birth-weight prematurely born children: a controlled study. Pediatr Dent 9:221\u2013225."},{"key":"SEOW-ETAL-1999","unstructured":"Seow WK, Amaratunge A, Sim R, Wan A -1999- Prevalence of caries in urban Australian aborigines aged 1-3.5 years. Pediatr Dent 21:91\u201396."},{"key":"WAN-ETAL-2001A","doi-asserted-by":"publisher","DOI":"10.1177\/00220345010800101601"},{"key":"WAN-ETAL-2001B","doi-asserted-by":"publisher","DOI":"10.1177\/00220345010800120701"},{"key":"WAN-ETAL-2002","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.2002.tb00298.x"}],"container-title":["Journal of Dental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/154405910308200703","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/154405910308200703","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/154405910308200703","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:00:18Z","timestamp":1777496418000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/154405910308200703"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,7]]},"references-count":18,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2003,7]]}},"alternative-id":["10.1177\/154405910308200703"],"URL":"https:\/\/doi.org\/10.1177\/154405910308200703","relation":{},"ISSN":["0022-0345","1544-0591"],"issn-type":[{"value":"0022-0345","type":"print"},{"value":"1544-0591","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,7]]}}}