{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T12:18:24Z","timestamp":1777810704335,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T00:00:00Z","timestamp":1101859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[2004,12]]},"abstract":"<jats:p>Fimbriae, which are involved in adherence, constitute an important pathogenic factor of Porphyromonas gingivalis. In vivo, however, the distribution of P. gingivalis-carrying fimbriae is unknown. The localization of P. gingivalis-carrying fimbriae was examined in situ. From 19 patients with severe periodontitis and P. gingivalis, we obtained 20 teeth with periodontal tissue attached, with and without immunolocalized fimbriae. Eleven teeth were subjected to light microscopy, 9 to electron microscopy. In 6 of the 11 samples examined, we detected positive reactions with an anti- P. gingivalis-fimbriae serum, located in the cementum-attached plaque area in the deep pocket zones. In the so-called \u2018plaque-free zones\u2019, P. gingivalis-carrying fimbriae were immunocytochemically observed to reside in contact with the dental cuticle in 6 of the 9 samples examined. These findings suggest that P. gingivalis-carrying fimbriae are strongly related to adherence to the root surface at the bottoms of human periodontal pockets.<\/jats:p>","DOI":"10.1177\/154405910408301210","type":"journal-article","created":{"date-parts":[[2009,1,8]],"date-time":"2009-01-08T19:39:42Z","timestamp":1231443582000},"page":"941-945","source":"Crossref","is-referenced-by-count":43,"title":["Localization of\n                    <i>Porphyromonas gingivalis<\/i>\n                    -carrying Fimbriae\n                    <i>in situ<\/i>\n                    in Human Periodontal Pockets"],"prefix":"10.1177","volume":"83","author":[{"given":"Y.","family":"Noiri","sequence":"first","affiliation":[{"name":"Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, 1\u20138 Yamadaoka, Suita, Osaka 565-0871, Japan; and"},{"name":"Department of Microbiology, School of Dentistry, Aichi-Gakuin University, Nagoya, Aichi 464-8650, Japan;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, 1\u20138 Yamadaoka, Suita, Osaka 565-0871, Japan; and"},{"name":"Department of Microbiology, School of Dentistry, Aichi-Gakuin University, Nagoya, Aichi 464-8650, Japan;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Yoshimura","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, 1\u20138 Yamadaoka, Suita, Osaka 565-0871, Japan; and"},{"name":"Department of Microbiology, School of Dentistry, Aichi-Gakuin University, Nagoya, Aichi 464-8650, Japan;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Ebisu","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, 1\u20138 Yamadaoka, Suita, Osaka 565-0871, Japan; and"},{"name":"Department of Microbiology, School of Dentistry, Aichi-Gakuin University, Nagoya, Aichi 464-8650, Japan;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2004,12,1]]},"reference":[{"key":"ABBAS-ETAL-1991","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1991.tb00439.x"},{"key":"AMANO-ETAL-1999","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.5.1426-1430.1999"},{"key":"CARRASSI-ETAL-1989","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1989.tb01652.x"},{"key":"EIDE-ETAL-1984","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1984.tb00909.x"},{"key":"FRIEDMAN-ETAL-1993","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1993.64.6.520"},{"key":"HIROSE-ETAL-1997","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.1997.tb01168.x"},{"key":"KOBAYASHI-AND-ROSE-1979","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1979.tb00781.x"},{"key":"KOLENBRANDER-ETAL-2002","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.66.3.486-505.2002"},{"key":"LAMONT-AND-JENKINSON-1998","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.62.4.1244-1263.1998"},{"key":"LOPEZ-ETAL-1990","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1990.61.2.95"},{"key":"MORDAN-ETAL-1999","unstructured":"Mordan NJ, Newman HN, Slaney JM, Curtis MA -1999- The apical plaque border in health and disease. In: Dental plaque revisited\u2014oral biofilms in health and disease. Proceedings of a conference held at the Royal College of Physicians, Nov 3\u20135, 1999, London, UK. Newman HN, Wilson M, editors. Cardiff, UK: Bioline, pp. 343\u2013374."},{"key":"NAKAGAWA-ETAL-2000","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.5.1909-1914.2000"},{"key":"NOIRI-AND-EBISU-2000","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.8.1319"},{"key":"NOIRI-ETAL-1997","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1997.tb00937.x"},{"key":"NOIRI-ETAL-2001","doi-asserted-by":"publisher","DOI":"10.1177\/00220345010800101301"},{"key":"SOJAR-ETAL-2004","doi-asserted-by":"publisher","DOI":"10.1016\/j.biochi.2004.04.007"},{"key":"SUZUKI-ETAL-1988","doi-asserted-by":"crossref","unstructured":"Suzuki Y, Yoshimura F, Takahashi K, Tani H, Suzuki T -1988- Detection of fimbriae and fimbrial antigens on the oral anaerobic\n                      Bacteroides gingivalis\n                      by negative staining and serological methods. 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