{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:05:22Z","timestamp":1791813922323,"version":"4.3.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[2005,1]]},"abstract":"<jats:p>In the treatment of dysgeusia, the use of zinc has been frequently tried, with equivocal results. The aim of the present randomized clinical trial, which involved a sufficiently large sample, was therefore to determine the efficacy of zinc treatment. Fifty patients with idiopathic dysgeusia were carefully selected. Zinc gluconate (140 mg\/day; n = 26) or placebo (lactose; n = 24) was randomly assigned to the patients. The patients on zinc improved in terms of gustatory function (p &lt; 0.001) and rated the dysgeusia as being less severe (p &lt; 0.05). Similarly, signs of depression in the zinc group were less severe (Beck Depression Inventory, p &lt; 0.05; mood scale, p &lt; 0.05). With the exception of the salivary calcium level, which was higher in the zinc patients (p &lt; 0.05), no other significant group differences were found. In conclusion, zinc appears to improve general gustatory function and, consequently, general mood scores in dysgeusia patients.<\/jats:p>","DOI":"10.1177\/154405910508400105","type":"journal-article","created":{"date-parts":[[2009,1,8]],"date-time":"2009-01-08T19:39:42Z","timestamp":1231443582000},"page":"35-38","source":"Crossref","is-referenced-by-count":117,"title":["Zinc Gluconate in the Treatment of Dysgeusia\u2014a Randomized Clinical Trial"],"prefix":"10.1177","volume":"84","author":[{"given":"S.M.","family":"Heckmann","sequence":"first","affiliation":[{"name":"School of Dental Medicine, University of Erlangen-Nuremberg, Gl\u00fcckstr. 11, 91054 Erlangen, Germany;"},{"name":"Dept. of Dental Public Health Sciences, School of Dentistry, University of Washington, Seattle, USA;"},{"name":"Dept. of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-University, Munich, Germany;"},{"name":"Dept. of Neurology, University of Erlangen-Nuremberg, Germany; and"},{"name":"Smell & Taste Clinic, Dept. of Otorhinolaryngology, University of Dresden, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Hujoel","sequence":"additional","affiliation":[{"name":"School of Dental Medicine, University of Erlangen-Nuremberg, Gl\u00fcckstr. 11, 91054 Erlangen, Germany;"},{"name":"Dept. of Dental Public Health Sciences, School of Dentistry, University of Washington, Seattle, USA;"},{"name":"Dept. of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-University, Munich, Germany;"},{"name":"Dept. of Neurology, University of Erlangen-Nuremberg, Germany; and"},{"name":"Smell & Taste Clinic, Dept. of Otorhinolaryngology, University of Dresden, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Habiger","sequence":"additional","affiliation":[{"name":"School of Dental Medicine, University of Erlangen-Nuremberg, Gl\u00fcckstr. 11, 91054 Erlangen, Germany;"},{"name":"Dept. of Dental Public Health Sciences, School of Dentistry, University of Washington, Seattle, USA;"},{"name":"Dept. of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-University, Munich, Germany;"},{"name":"Dept. of Neurology, University of Erlangen-Nuremberg, Germany; and"},{"name":"Smell & Taste Clinic, Dept. of Otorhinolaryngology, University of Dresden, Germany;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Friess","sequence":"additional","affiliation":[{"name":"School of Dental Medicine, University of Erlangen-Nuremberg, Gl\u00fcckstr. 11, 91054 Erlangen, Germany;"},{"name":"Dept. of Dental Public Health Sciences, School of Dentistry, University of Washington, Seattle, USA;"},{"name":"Dept. of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-University, Munich, Germany;"},{"name":"Dept. of Neurology, University of Erlangen-Nuremberg, Germany; 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