{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T12:24:45Z","timestamp":1777811085415,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2005,4,1]],"date-time":"2005-04-01T00:00:00Z","timestamp":1112313600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[2005,4]]},"abstract":"<jats:p>EL\/Sea mice have 100% incidence of the absence of third molars (M3). Our previous linkage analysis using EL\/Sea and MSM\/Msf mouse strains provides statistical evidence of a major locus for the absence of M3, designated am3, of EL\/Sea at the middle region of chromosome 3. To obtain independent evidence for linkage and more precisely determine the location of the am3 locus, we generated EL\/Sea congenic strains for am3 in which the restricted interval of chromosome 3 of EL\/Sea was replaced by an MSM\/Msf-derived homologue. EL\/Sea congenic mice that were either heterozygous or homozygous for the MSM\/Msf-derived interval exhibited a significant decrease in the incidence of the absence of third molars, confirming previous genome scan results. These results confine the am3 locus to an approximately 4.4-cM region, and demonstrate that other unmapped genes are also involved in the absence of M3 in EL\/Sea mice.<\/jats:p>","DOI":"10.1177\/154405910508400404","type":"journal-article","created":{"date-parts":[[2009,1,8]],"date-time":"2009-01-08T19:39:42Z","timestamp":1231443582000},"page":"315-319","source":"Crossref","is-referenced-by-count":8,"title":["Localization of\n                    <i>am3<\/i>\n                    using EL Congenic Mouse Strains"],"prefix":"10.1177","volume":"84","author":[{"given":"T.","family":"Shimizu","sequence":"first","affiliation":[{"name":"Department of Pediatric Dentistry, Nihon University School of Dentistry at Matsudo, 2-870-1 Sakaecho-Nishi, Matsudo, Chiba 271-8587, Japan; and"},{"name":"Department of Pediatric Dentistry, Tsurumi University School of Dental Medicine, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama 230-8501, Japan;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry, Nihon University School of Dentistry at Matsudo, 2-870-1 Sakaecho-Nishi, Matsudo, Chiba 271-8587, Japan; and"},{"name":"Department of Pediatric Dentistry, Tsurumi University School of Dental Medicine, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama 230-8501, Japan;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Asada","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry, Nihon University School of Dentistry at Matsudo, 2-870-1 Sakaecho-Nishi, Matsudo, Chiba 271-8587, Japan; and"},{"name":"Department of Pediatric Dentistry, Tsurumi University School of Dental Medicine, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama 230-8501, Japan;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Okamoto","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry, Nihon University School of Dentistry at Matsudo, 2-870-1 Sakaecho-Nishi, Matsudo, Chiba 271-8587, Japan; and"},{"name":"Department of Pediatric Dentistry, Tsurumi University School of Dental Medicine, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama 230-8501, Japan;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Maeda","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry, Nihon University School of Dentistry at Matsudo, 2-870-1 Sakaecho-Nishi, Matsudo, Chiba 271-8587, Japan; and"},{"name":"Department of Pediatric Dentistry, Tsurumi University School of Dental Medicine, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama 230-8501, Japan;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2005,4,1]]},"reference":[{"key":"ARTE-ETAL-1996","doi-asserted-by":"publisher","DOI":"10.1177\/00220345960750060401"},{"key":"ASADA-ETAL-2000","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-263x.2000.00168.x"},{"key":"FRAZIER-BOWERS-ETAL-2002","doi-asserted-by":"publisher","DOI":"10.1177\/0810129"},{"key":"GOLDENBERG-ETAL-2000","doi-asserted-by":"publisher","DOI":"10.1177\/00220345000790070701"},{"key":"JUMLONGRAS-ETAL-2001","doi-asserted-by":"publisher","DOI":"10.1086\/321271"},{"key":"KRATOCHWIL-ETAL-2002","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1035602"},{"key":"KRONMILLER-ETAL-1991","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(91)90307-O"},{"key":"LAIRD-ETAL-1991","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/19.15.4293"},{"key":"LIDRAL-AND-REISING-2002","doi-asserted-by":"publisher","DOI":"10.1177\/154405910208100410"},{"key":"MARKEL-ETAL-1997","doi-asserted-by":"publisher","DOI":"10.1038\/ng1197-280"},{"key":"MILLER-1978","unstructured":"Miller WA -1978- The dentitions of tabby and crinkled mice. 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