{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T12:15:04Z","timestamp":1791029704908,"version":"4.1.0"},"reference-count":32,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2006,10,1]],"date-time":"2006-10-01T00:00:00Z","timestamp":1159660800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:p>Although the contribution of the oral microbiota to oral malodor is well-documented, the potential role of Gram-positive micro-organisms is unclear. In the current study, we tested the hypothesis that Gram-positive micro-organisms contribute to malodor production by deglycosylating oral glycoproteins, rendering them susceptible to subsequent proteolysis. To this end, we examined the effect of Streptococcus salivarius on Porphyromonas gingivalis-mediated putrefaction of a model glycoprotein (pig gastric mucin). Malodor was scored by two odor judges, and volatile sulfides were determined with the use of a sulfide monitor. Mucin degradation was followed by electrophoresis on SDS-PAGE. Results showed that the addition of S. salivarius or \u03b2-galactosidase promoted mucin degradation and concomitant malodor production. Addition of glycosidic inhibitors (p-APTG and glucose) inhibited this process. These results suggest that Gram-positive micro-organisms such as S. salivarius contribute to oral malodor production by deglycosylating salivary glycoproteins, thus exposing their protein core to further degradation by Gram-negative micro-organisms.<\/jats:p>","DOI":"10.1177\/154405910608501007","type":"journal-article","created":{"date-parts":[[2009,1,8]],"date-time":"2009-01-08T19:39:42Z","timestamp":1231443582000},"page":"910-914","source":"Crossref","is-referenced-by-count":48,"title":["<i>Streptococcus salivarius<\/i>\n                    Promotes Mucin Putrefaction and Malodor Production by\n                    <i>Porphyromonas gingivalis<\/i>"],"prefix":"10.1177","volume":"85","author":[{"given":"N.","family":"Sterer","sequence":"first","affiliation":[{"name":"Department of Prosthodontics, the Hebrew University-Hadassah School of Dental Medicine, POB 12272, Jerusalem 91120, Israel; and"},{"name":"Department of Human Microbiology and Goldschleger School of Dental Medicine, Sackler Faculty of Medicine, Tel-Aviv University, Ramat-Aviv, Israel, 69978"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Rosenberg","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, the Hebrew University-Hadassah School of Dental Medicine, POB 12272, Jerusalem 91120, Israel; and"},{"name":"Department of Human Microbiology and Goldschleger School of Dental Medicine, Sackler Faculty of Medicine, Tel-Aviv University, Ramat-Aviv, Israel, 69978"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2006,10,1]]},"reference":[{"key":"AAS-ETAL-2005","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.11.5721-5732.2005"},{"key":"BERG-AND-FOSDICK-1946","doi-asserted-by":"publisher","DOI":"10.1177\/00220345460250020301"},{"key":"CLAESSON-ETAL-1990","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1990.tb00411.x"},{"key":"DE-BOEVER-AND-LOESCHE-1995","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1995.0049"},{"key":"DE-JONG-AND-VAN-DER-HOEVEN-1987","doi-asserted-by":"publisher","DOI":"10.1177\/00220345870660021901"},{"key":"DE-JONG-ETAL-1984","doi-asserted-by":"publisher","DOI":"10.1128\/aem.47.5.901-904.1984"},{"key":"DUNNETT-1955","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1955.10501294"},{"key":"FOSDICK-AND-PIEZ-1953","doi-asserted-by":"publisher","DOI":"10.1177\/00220345530320012301"},{"key":"GOLDBERG-ETAL-1994","doi-asserted-by":"publisher","DOI":"10.1177\/00220345940730060701"},{"key":"GOLDBERG-ETAL-1997","unstructured":"Goldberg S, Kozlovsky A, Rosenberg M -1997- Association of diamines with oral malodor. 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