{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:09:14Z","timestamp":1777853354633,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2008,3,1]],"date-time":"2008-03-01T00:00:00Z","timestamp":1204329600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the International Association of Physicians in AIDS Care"],"published-print":{"date-parts":[[2008,3]]},"abstract":"<jats:p>The rationale to screen for glucose-6-phosphate dehydrogenase (G6PD) deficiency in HIV-infected individuals is their increased likelihood to receive oxidant drugs and subsequent potential of hemolytic events. However, current guidelines regarding who should be screened are conflicting. The authors examined the prevalence of G6PD deficiency and the frequency of hemolytic events in an urban HIV clinic. They used data from a military database as a comparison. In both cohorts, a relatively high number of black females were found to be G6PD deficient (10% and 13%), which was similar to the rate in men (15% and 12%). No white females were G6PD deficient. The authors identified 8 drug-related hemolytic events in HIV clinic patients. Two patients necessitated blood transfusions; both were triggered by trimethoprim\/sulfamethoxazole (TMP\/SMX). Although G6PD screening prior to the use of TMP\/SMX is not often considered by clinicians, the authors' finding of 2 hemolytic events requiring transfusion suggests this would be beneficial.<\/jats:p>","DOI":"10.1177\/1545109708315324","type":"journal-article","created":{"date-parts":[[2008,3,18]],"date-time":"2008-03-18T21:44:04Z","timestamp":1205876644000},"page":"88-90","source":"Crossref","is-referenced-by-count":15,"title":["Prevalence and Significance of G6PD Deficiency in Patients of an Urban HIV Clinic"],"prefix":"10.1177","volume":"7","author":[{"given":"Marisa","family":"Tungsiripat","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Cleveland Clinic Foundation, Cleveland, OH,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henning","family":"Drechsler","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, University of Texas Southwestern Medical Center, Dallas TX, VA North Texas Health Care Center, Dallas, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Sarlone","sequence":"additional","affiliation":[{"name":"University of Tennessee, Memphis"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathleen","family":"Amyot","sequence":"additional","affiliation":[{"name":"Department of Family Practice, Saint Louis University\/Scott AFB, St. Louis, MO"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Laffey","sequence":"additional","affiliation":[{"name":"Department of Family Practice, Saint Louis University, St. Louis, MO"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith","family":"Aberg","sequence":"additional","affiliation":[{"name":"New York University, New York, NY, AIDS Clinical Trials Unit, Seattle, WA, Bellevue Hospital Center, New York, NY"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2008,3,4]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1974.03230250032024"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1093\/milmed\/138.3.153"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197004022821402"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197905033001801"},{"issue":"9","key":"atypb5","first-page":"905","volume":"171","author":"Chinevere TD","year":"2006","journal-title":"S. Army personnel. Mil Med"},{"issue":"8","key":"atypb6","first-page":"1","volume":"51","author":"Kaplan JE","year":"2002","journal-title":"MMWR Recomm Rep."},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1521\/aeap.17.2.6.58697"},{"key":"atypb8","volume-title":"2005-2006 Medical Management of HIV Infection","author":"Bartlett JG","year":"2005"},{"key":"atypb9","volume-title":"The Sanford Guide to HIV\/AIDS Therapy 2006-2007","author":"Antimicrobial Therapy.","year":"2006","edition":"15"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1086\/423390"}],"container-title":["Journal of the International Association of Physicians in AIDS Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1545109708315324","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1545109708315324","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:51:40Z","timestamp":1777503100000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1545109708315324"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,3]]}},"alternative-id":["10.1177\/1545109708315324"],"URL":"https:\/\/doi.org\/10.1177\/1545109708315324","relation":{},"ISSN":["1545-1097"],"issn-type":[{"value":"1545-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2008,3]]}}}