{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:09:43Z","timestamp":1777853383503,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the International Association of Physicians in AIDS Care"],"published-print":{"date-parts":[[2010,1]]},"abstract":"<jats:p>\n                    Epidermodysplasia verruciformis (EV) is a rare disorder characterized by persistent human papillomavirus (HPV) infection. Here, we describe a 48-year-old, black, married male with AIDS, presenting a 1-year history of asymptomatic hypopigmented lesions that appeared 3 years after antiretroviral therapy (ART) initiation. Pre-ART, the initial CD4 count was 32 cells\/mm\n                    <jats:sup>3<\/jats:sup>\n                    and the skin lesions appeared when the CD4 count reached 122 cells\/mm\n                    <jats:sup>3<\/jats:sup>\n                    . Dermatological examination demonstrated thin, scaly, slightly verrucous hypopigmented macules and papules, isolated or presenting with a linear aspect (K\u00f6bner phenomenon) in some areas, distributed on the neck, trunk, and superior and inferior members. Skin biopsy of a macular lesion revealed epidermal acanthosis with vacuolated keratinocytes presenting blue-gray pallor, arranged in clusters at the granular and upper spinous layer. Immunohistochemistry revealed expression of p16\n                    <jats:sup>INK4a<\/jats:sup>\n                    with diffuse positivity in the upper third of the epithelium, corresponding to the vacuolated keratinocytes. Polymerase chain reaction (PCR) was positive for type 12 HPV, and a diagnosis of EV-like associated to AIDS was made. EV-like is a rare disease and in this patent might be a manifestation of immune reconstitution inflammatory syndrome.\n                  <\/jats:p>","DOI":"10.1177\/1545109709355709","type":"journal-article","created":{"date-parts":[[2010,1,13]],"date-time":"2010-01-13T14:00:18Z","timestamp":1263391218000},"page":"10-14","source":"Crossref","is-referenced-by-count":3,"title":["Post-ART Epidermodysplasia Verruciformis in a Patient With AIDS"],"prefix":"10.1177","volume":"9","author":[{"given":"Leila Cristina","family":"Ferreira da Silva","sequence":"first","affiliation":[{"name":"Enfermeira do Servi\u00e7o de Assist\u00eancia Especializada em DST\/AIDS, Ger\u00eancia de Dermatologia e DST\/AIDS, Funda\u00e7\u00e3o de Medicina Tropical do Amazonas (FMTAM), Amazonas, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelica","family":"Espinosa Miranda","sequence":"additional","affiliation":[{"name":"N\u00facleo de Doen\u00e7as Infecciosas, Universidade Federal do Esp\u00edrito Santo, Amazonas, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz Carlos","family":"de Lima Ferreira","sequence":"additional","affiliation":[{"name":"Ger\u00eancia de Anatomia Patol\u00f3gica, FMTAM, Amazonas, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"Roberto","family":"Moreira da Silva","sequence":"additional","affiliation":[{"name":"Ger\u00eancia de Anatomia Patol\u00f3gica, FMTAM, Amazonas, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelo","family":"T\u00e1vora Mira","sequence":"additional","affiliation":[{"name":"Centro de Ci\u00eancias da Sa\u00fade e Biol\u00f3gicas, Universidade Pontif\u00edcia Cat\u00f3lica. Amazonas, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina","family":"Talhari","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Assist\u00eancia Especializada em DST\/AIDS, Ger\u00eancia de Dermatologia e DST\/AIDS, FMTAM, Amazonas, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sin\u00e9sio","family":"Talhari","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Assist\u00eancia Especializada em DST\/AIDS, Ger\u00eancia de Dermatologia e DST\/AIDS, FMTAM, Amazonas, Brazil,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,1,13]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1044"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20071311"},{"key":"atypb3","first-page":"157","volume":"120","author":"Orth G.","year":"1986","journal-title":"Ciba Found Symp"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.24.11636-11641.2000"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2006.03014.x"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1002\/1096-9071(200007)61:3<289::AID-JMV2>3.0.CO;2-Z"},{"issue":"4","key":"atypb7","first-page":"307","volume":"79","author":"Hultgren TL","year":"2007","journal-title":"Cutis"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2003.00703.x"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1992.tb03764.x"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1097\/01.aids.0000161769.06158.8a"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1186\/1742-6405-4-9"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.47276\/lr.78.2.151"}],"container-title":["Journal of the International Association of Physicians in AIDS Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1545109709355709","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1545109709355709","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:52:05Z","timestamp":1777503125000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1545109709355709"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,1]]}},"alternative-id":["10.1177\/1545109709355709"],"URL":"https:\/\/doi.org\/10.1177\/1545109709355709","relation":{},"ISSN":["1545-1097"],"issn-type":[{"value":"1545-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2010,1]]}}}