{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T19:10:22Z","timestamp":1790363422229,"version":"4.1.0"},"reference-count":40,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2014,3,18]],"date-time":"2014-03-18T00:00:00Z","timestamp":1395100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Neurorehabil Neural Repair"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:p>\n                    <jats:italic toggle=\"yes\">Background<\/jats:italic>\n                    . Action observation has been suggested as a possible gateway to retraining arm motor function post stroke. However, it is unclear if the neuronal response to action observation is affected by stroke and if it changes during the course of recovery.\n                    <jats:italic toggle=\"yes\">Objective<\/jats:italic>\n                    . To examine longitudinal changes in neuronal activity in a group of patients with subacute stroke when observing and executing a bimanual movement task.\n                    <jats:italic toggle=\"yes\">Methods<\/jats:italic>\n                    . Eighteen patients were examined twice using 3-T functional magnetic resonance imaging; 1 to 2 weeks and 3 months post stroke symptom onset. Eighteen control participants were examined once. Image time series were analyzed (SPM8) and correlated with clinical motor function scores.\n                    <jats:italic toggle=\"yes\">Results<\/jats:italic>\n                    . During action observation and execution, an overlap of neuronal activation was observed in the superior and inferior parietal lobe, precentral gyrus, insula, and inferior temporal gyrus in both control participants and patients (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; .05; false discovery rate corrected). The neuronal response in the observation task increased from 1 to 2 weeks to 3 months after stroke. Most activated clusters were observed in the inferior temporal gyrus, the thalamus and movement-related areas, such as the premotor, supplementary and motor cortex (BA4, BA6). Increased activation of cerebellum and premotor area correlated with improved arm motor function. Most patients had regained full movement ability.\n                    <jats:italic toggle=\"yes\">Conclusions<\/jats:italic>\n                    . Plastic changes in neurons responding to action observation and action execution occurred in accordance with clinical recovery. The involvement of motor areas when observing actions early and later after stroke may constitute a possible access to the motor system.\n                  <\/jats:p>","DOI":"10.1177\/1545968314527350","type":"journal-article","created":{"date-parts":[[2014,3,18]],"date-time":"2014-03-18T23:37:13Z","timestamp":1395185833000},"page":"874-884","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":56,"title":["Plasticity and Response to Action Observation"],"prefix":"10.1177","volume":"28","author":[{"given":"Iris C.","family":"Brunner","sequence":"first","affiliation":[{"name":"University of Bergen, Bergen, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan Sture","family":"Skouen","sequence":"additional","affiliation":[{"name":"University of Bergen, Bergen, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Ersland","sequence":"additional","affiliation":[{"name":"Haukeland University Hospital, Bergen, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renate","family":"Gr\u00fcner","sequence":"additional","affiliation":[{"name":"University of Bergen, Bergen, Norway"},{"name":"Haukeland University Hospital, Bergen, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,3,18]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-4949.2007.00093.x"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2011.10.023"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2007.03.043"},{"key":"e_1_3_3_5_2","first-page":"313","article-title":"Mirror neurons: action observation treatment as a tool in stroke rehabilitation","volume":"48","author":"Franceschini M","year":"2012","unstructured":"Franceschini M, Agosti M, Cantagallo A, Sale P, Mancuso M, Buccino G. Mirror neurons: action observation treatment as a tool in stroke rehabilitation. Eur J Phys Rehabil Med. 2012;48:313-318.","journal-title":"Eur J Phys Rehabil Med"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/1545968311427406"},{"key":"e_1_3_3_7_2","first-page":"85","article-title":"Resonance behaviors and mirror neurons","volume":"137","author":"Rizzolatti G","year":"1999","unstructured":"Rizzolatti G, Fadiga L, Fogassi L, Gallese V. Resonance behaviors and mirror neurons. Arch Ital Biol. 1999;137:85-100.","journal-title":"Arch Ital Biol"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bandl.2007.11.002"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/119.2.593"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2011.07.004"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2009.12.112"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.50.6.714"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1191\/0269215505cr832oa"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.5014\/ajot.57.5.570"},{"key":"e_1_3_3_15_2","volume-title":"Paper presented at: 12th Annual Meeting of the Organization for Human Brain Mapping","author":"Alem\u00e1n-G\u00f3mez Y","unstructured":"Alem\u00e1n-G\u00f3mez Y, Melie-Garc\u00eda L, Vald\u00e9s-Hernandez P. IBASPM: Toolbox for automatic parcellation of brain structures. Paper presented at: 12th Annual Meeting of the Organization for Human Brain Mapping; June 11-15, 2006; Florence, Italy."},{"key":"e_1_3_3_16_2","volume-title":"Co-Planar Stereotaxic Atlas of the Human Brain 3-Dimensional Proportional System: An Approach to Cerebral Imaging","author":"Talairach J","year":"1988","unstructured":"Talairach J, Tournoux P. Co-Planar Stereotaxic Atlas of the Human Brain 3-Dimensional Proportional System: An Approach to Cerebral Imaging. Stuttgart, Germany: George Thieme Verlag; 1988."},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.20345"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0193(200007)10:3<120::AID-HBM30>3.0.CO;2-8"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awl090"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.001105"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-002-0604-1"},{"key":"e_1_3_3_22_2","volume-title":"Neuroscience. Exploring the Brain","author":"Bear MF","year":"2007","unstructured":"Bear MF, Connors BW, Paradiso MA. Neuroscience. Exploring the Brain. 3rd ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2007.","edition":"3"},{"key":"e_1_3_3_23_2","first-page":"285","article-title":"Future perspectives in functional neuroimaging in stroke recovery","volume":"43","author":"Ward NS","year":"2007","unstructured":"Ward NS. Future perspectives in functional neuroimaging in stroke recovery. Eura Medicophys. 2007;43:285-294.","journal-title":"Eura Medicophys"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awg145"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1177\/1545968308322840"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410310502"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1177\/1545968310364058"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2003.12.011"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awf148"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awf282"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.27.070203.144230"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2001.01385.x"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2009.12.112"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhn181"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1002\/dev.20504"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1177\/1545968304274351"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1162\/089892904322755601"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhi007"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000238594.91938.1e"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.3233\/RNN-130332"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2735"}],"container-title":["Neurorehabilitation and Neural Repair"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1545968314527350","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1545968314527350","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1545968314527350","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T07:05:21Z","timestamp":1777705521000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1545968314527350"}},"subtitle":["A Longitudinal fMRI Study of Potential Mirror Neurons in Patients With Subacute Stroke"],"short-title":[],"issued":{"date-parts":[[2014,3,18]]},"references-count":40,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["10.1177\/1545968314527350"],"URL":"https:\/\/doi.org\/10.1177\/1545968314527350","relation":{},"ISSN":["1545-9683","1552-6844"],"issn-type":[{"value":"1545-9683","type":"print"},{"value":"1552-6844","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,18]]}}}