{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T21:43:24Z","timestamp":1791755004989,"version":"4.3.4"},"reference-count":48,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,5,21]],"date-time":"2020-05-21T00:00:00Z","timestamp":1590019200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1102272"],"award-info":[{"award-number":["1102272"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1125054"],"award-info":[{"award-number":["1125054"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008717","name":"Sylvia and Charles Viertel Charitable Foundation","doi-asserted-by":"publisher","award":["100008717"],"award-info":[{"award-number":["100008717"]}],"id":[{"id":"10.13039\/100008717","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Neurorehabil Neural Repair"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:p>\n                    Background. Resting state functional connectivity (RSFC) is a developmental priority for stroke recovery. Objective. To determine whether (1) RSFC differs between stroke survivors based on integrity of descending motor pathways; (2) RSFC is associated with upper-limb behavior in chronic stroke; and (3) the relationship between interhemispheric RSFC and upper-limb behavior differs based on descending motor pathway integrity. Methods. A total of 36 people with stroke (aged 64.4 \u00b1 11.1 years, time since stroke 4.0 \u00b1 2.8 years) and 25 healthy adults (aged 67.3 \u00b1 6.7 years) participated in this study. RSFC was estimated from electroencephalography (EEG) recordings. Integrity of descending motor pathways was ascertained using transcranial magnetic stimulation to determine motor-evoked potential (MEP) status and magnetic resonance imaging to determine lesion overlap and fractional anisotropy of the corticospinal tract (CST). For stroke participants, upper-limb motor behavior was assessed using the Fugl-Meyer test, Action Research Arm Test and grip strength. Results. \u03b2-Frequency interhemispheric sensorimotor RSFC was greater for MEP+ stroke participants compared with MEP\u2212 ( P = .020). There was a significant positive correlation between \u03b2 RSFC and upper-limb behavior ( P = .004) that appeared to be primarily driven by the MEP+ group. A hierarchical regression identified that the addition of \u03b2 RSFC to measures of CST integrity explained greater variance in upper-limb behavior ( R\n                    <jats:sup>2<\/jats:sup>\n                    change = 0.13; P = .01). Conclusions. This study provides insight to understand the role of EEG-based measures of interhemispheric network activity in chronic stroke. Resting state interhemispheric connectivity was positively associated with upper-limb behavior for stroke survivors where residual integrity of descending motor pathways was maintained.\n                  <\/jats:p>","DOI":"10.1177\/1545968320921824","type":"journal-article","created":{"date-parts":[[2020,5,21]],"date-time":"2020-05-21T07:14:38Z","timestamp":1590045278000},"page":"547-557","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":40,"title":["Resting State Functional Connectivity Is Associated With Motor Pathway Integrity and Upper-Limb Behavior in Chronic Stroke"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7129-6684","authenticated-orcid":false,"given":"Brenton","family":"Hordacre","sequence":"first","affiliation":[{"name":"University of South Australia, IIMPACT in Health, Adelaide, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchell R.","family":"Goldsworthy","sequence":"additional","affiliation":[{"name":"Lifespan Human Neurophysiology group, Adelaide Medical School, The University of Adelaide, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellana","family":"Welsby","sequence":"additional","affiliation":[{"name":"University of South Australia, IIMPACT in Health, Adelaide, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynton","family":"Graetz","sequence":"additional","affiliation":[{"name":"Lifespan Human Neurophysiology group, Adelaide Medical School, The University of Adelaide, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Ballinger","sequence":"additional","affiliation":[{"name":"Lifespan Human Neurophysiology group, Adelaide Medical School, The University of Adelaide, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Hillier","sequence":"additional","affiliation":[{"name":"University of South Australia, IIMPACT in Health, Adelaide, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,5,21]]},"reference":[{"key":"bibr1-1545968320921824","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e31823ac046"},{"key":"bibr2-1545968320921824","doi-asserted-by":"publisher","DOI":"10.1177\/1747493017714176"},{"key":"bibr3-1545968320921824","doi-asserted-by":"publisher","DOI":"10.1177\/1747493016643851"},{"key":"bibr4-1545968320921824","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/aws146"},{"key":"bibr5-1545968320921824","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awv156"},{"key":"bibr6-1545968320921824","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.24079"},{"key":"bibr7-1545968320921824","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2010.12.037"},{"key":"bibr8-1545968320921824","doi-asserted-by":"publisher","DOI":"10.1097\/00004356-198112000-00001"},{"key":"bibr9-1545968320921824","doi-asserted-by":"publisher","DOI":"10.1111\/1440-1630.12527"},{"key":"bibr10-1545968320921824","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/46.4.357"},{"key":"bibr11-1545968320921824","doi-asserted-by":"publisher","DOI":"10.1177\/154596802401105171"},{"key":"bibr12-1545968320921824","doi-asserted-by":"publisher","DOI":"10.1191\/026921599676433080"},{"key":"bibr13-1545968320921824","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2003.10.009"},{"key":"bibr14-1545968320921824","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/156869"},{"key":"bibr15-1545968320921824","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2016.10.031"},{"key":"bibr16-1545968320921824","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2011.01.055"},{"key":"bibr17-1545968320921824","doi-asserted-by":"publisher","DOI":"10.3389\/fnsys.2015.00175"},{"key":"bibr18-1545968320921824","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2016.02.012"},{"key":"bibr19-1545968320921824","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2004.07.051"},{"key":"bibr20-1545968320921824","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2011.09.015"},{"key":"bibr21-1545968320921824","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.2002.1132"},{"key":"bibr22-1545968320921824","doi-asserted-by":"publisher","DOI":"10.1016\/S1361-8415(01)00036-6"},{"key":"bibr23-1545968320921824","unstructured":"Andersson JL, Jenkinson M, Smith S. 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