{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T05:52:37Z","timestamp":1792821157226,"version":"4.5.0"},"reference-count":44,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2021,12,30]],"date-time":"2021-12-30T00:00:00Z","timestamp":1640822400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Neurorehabil Neural Repair"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Most of the current literature around amputation focuses on lower extremity amputation or engineering aspects of prosthetic devices. There is a need to more clearly understand neurobehavioral mechanisms related to upper extremity amputation and how such mechanisms might influence recovery and utilization of prostheses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This scoping review aims to identify and summarize the current literature on adult traumatic upper limb amputation in regard to recovery and functional outcomes and how neuroplasticity might influence these findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We identified appropriate articles using Academic Search Complete EBSCO, OVID Medline, and Cochrane databases. The resulting articles were then exported, screened, and reviewed based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Reviews (PRISMA-ScR) guidelines.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eleven (11) studies met the study criteria. Of these studies, 7 focused on sensory involvement, 3 focused on neuroplastic changes post-amputation related to functional impact, and 1 study focused on motor control and learning post-amputation. Overall, these studies revealed an incomplete understanding of the neural mechanisms involved in motor rehabilitation in the central and peripheral nervous systems, while also demonstrating the value of an individualized approach to neurorehabilitation in upper limb loss.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There is a gap in our understanding of the role of neurorehabilitation following amputation. Overall, focused rehabilitation parameters, demographic information, and clarity around central and peripheral neural mechanisms are needed in future research to address neurobehavioral mechanisms to promote functional recovery following traumatic upper extremity amputation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15459683211070277","type":"journal-article","created":{"date-parts":[[2021,12,30]],"date-time":"2021-12-30T06:27:59Z","timestamp":1640845679000},"page":"208-216","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Neurorehabilitation in Adults With Traumatic Upper Extremity Amputation: A Scoping Review"],"prefix":"10.1177","volume":"36","author":[{"given":"Jake","family":"Rydland","sequence":"first","affiliation":[{"name":"Division of Physical Therapy, Emory University School of Medicine, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Spiegel","sequence":"additional","affiliation":[{"name":"Division of Physical Therapy, Emory University School of Medicine, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia","family":"Wolfe","sequence":"additional","affiliation":[{"name":"Division of Physical Therapy, Emory University School of Medicine, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bennett","family":"Alterman","sequence":"additional","affiliation":[{"name":"School of Biological Sciences, Georgia Tech, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6332-6046","authenticated-orcid":false,"given":"John T","family":"Johnson","sequence":"additional","affiliation":[{"name":"School of Biological Sciences, Georgia Tech, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0771-0294","authenticated-orcid":false,"given":"Lewis A","family":"Wheaton","sequence":"additional","affiliation":[{"name":"School of Biological Sciences, Georgia Tech, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,12,30]]},"reference":[{"key":"bibr1-15459683211070277","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2007.11.005"},{"key":"bibr2-15459683211070277","volume-title":"US Department of Health and Human Services CDC","author":"Owings M"},{"key":"bibr3-15459683211070277","doi-asserted-by":"publisher","DOI":"10.1097\/PHM.0b013e3181587f6c"},{"key":"bibr4-15459683211070277","doi-asserted-by":"publisher","DOI":"10.1080\/17483100701869826"},{"key":"bibr5-15459683211070277","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2016.00209"},{"key":"bibr6-15459683211070277","doi-asserted-by":"publisher","DOI":"10.1007\/s10926-018-9757-y"},{"issue":"8","key":"bibr7-15459683211070277","first-page":"360","volume":"37","author":"Webster J","year":"2020","journal-title":"Fed Pract : For the Health Care Professionals of the VA, DoD, and PHS"},{"key":"bibr8-15459683211070277","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijotn.2020.100773"},{"key":"bibr9-15459683211070277","doi-asserted-by":"publisher","DOI":"10.1197\/j.jht.2007.09.006"},{"key":"bibr10-15459683211070277","doi-asserted-by":"publisher","DOI":"10.7326\/M18-0850"},{"key":"bibr11-15459683211070277","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/14.suppl_6.3"},{"key":"bibr12-15459683211070277","doi-asserted-by":"publisher","DOI":"10.5812\/traumamon.11693"},{"key":"bibr13-15459683211070277","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2018.04.017"},{"key":"bibr14-15459683211070277","unstructured":"Keisler-Starkey K, Bunch LN. 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