{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:01:22Z","timestamp":1777942882687,"version":"3.51.4"},"reference-count":66,"publisher":"SAGE Publications","issue":"10-11","license":[{"start":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T00:00:00Z","timestamp":1663632000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100031366","name":"ERA-Net Neuron","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100031366","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000156","name":"Fonds de Recherche du Qu\u00e9bec - Sant\u00e9","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000156","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007867","name":"Universite Laval","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100007867","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Neuroscience thematic research centre"},{"name":"Centre for Interdisciplinary Research in Rehabilitation and Social Integration"},{"name":"Fonds de recherche du Qu\u00e9bec Sant\u00e9"},{"name":"Emeritus Research Scholar Award from Fonds de recherche Qu\u00e9bec \u2013 Sant\u00e9"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Neurorehabil Neural Repair"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:p>The corticospinal tract has been shown to be involved in normal walking in humans. However, its contribution during more challenging locomotor tasks is still unclear. As the corticospinal tract can be a potential target to promote gait recovery after neurological injury, it is of primary importance to quantify its use during human walking. The aims of the current study were to: (1) quantify the effects of precision walking on corticospinal excitability as compared to normal walking; (2) assess if corticospinal modulation is related to task difficulty or participants\u2019 performance. Sixteen healthy participants walked on a treadmill during 2 tasks: regular walking (simple task) and stepping onto virtual targets (precision task). Virtual targets appeared randomly at 3 different step lengths: preferred, and \u00b120%. To assess corticospinal excitability, 25 motor evoked potentials (MEPs) were recorded from the tibialis anterior muscle in each task during walking. Performance for each participant (global success score; % of target hit) and task difficulty related to step length adjustments (success score for each step length) were also calculated. MEP size was larger during the precision task in all participants (mean increase of 93%\u2009\u00b1\u200972%; P\u2009&lt;\u2009.05) compared to the simple task. There was a correlation between MEP facilitation and individual performance ( r\u2009=\u2009\u2212.64; P\u2009&lt;\u2009.05), but no difference in MEP size associated with task difficulty ( P\u2009&gt;\u2009.05). In conclusion, corticospinal excitability exhibits a large increase during the precision task. This effect needs to be confirmed in neurological populations to potentially provide a simple and non-invasive approach to increase corticospinal drive during gait rehabilitation.<\/jats:p>","DOI":"10.1177\/15459683221124909","type":"journal-article","created":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T06:54:33Z","timestamp":1663656873000},"page":"689-700","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Corticospinal Excitability Quantification During a Visually-Guided Precision Walking Task in Humans: Potential for Neurorehabilitation"],"prefix":"10.1177","volume":"36","author":[{"given":"Charline","family":"Dambreville","sequence":"first","affiliation":[{"name":"Center for Interdisciplinary Research in Rehabilitation and Social Integration, Quebec City, QC, Canada"},{"name":"Neuroscience Thematic Research Center, Universit\u00e9 Laval, Quebec City, QC, 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