{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T23:05:43Z","timestamp":1787785543220,"version":"build-2784847793"},"reference-count":43,"publisher":"SAGE Publications","issue":"2-3","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["107-2314-B-002-049-MY3"],"award-info":[{"award-number":["107-2314-B-002-049-MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["107-2628-E-002 -004 -MY3"],"award-info":[{"award-number":["107-2628-E-002 -004 -MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Neurorehabil Neural Repair"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Previous studies have compared the effectiveness of constraint-induced movement therapy (CIMT) by different training doses. However, whether the dosing schedule, that is, intensive or distributed, influences the effectiveness of CIMT in children with unilateral cerebral palsy (CP) is unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the effectiveness of intensive and distributed CIMT for children with unilateral CP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Fifty children with unilateral CP were assigned to intensive or distributed CIMT group with a total of 36 training hours. The intensive CIMT was delivered within 1\u2009week, and the distributed CIMT was delivered twice a week for 8\u2009weeks. The outcomes were the Melbourne Assessment 2, Box and Block Test, Pediatric Motor Activity Log-Revised (PMAL-R), Bruininks\u2013Oseretsky test of motor proficiency 2, ABILHAND-Kids and Parenting Stress Index\u2014Short Form. The intensive group was assessed at the initiation of treatment (week 0), at the end of 1\u2009week treatment (week 1), and 8\u2009weeks after the initiation of treatment (week 8). The distributed group was assessed at week 0 and week 8.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The within-group analyses demonstrated significant differences on all motor outcomes. There were no significant between-group differences at post-treatment, while the intensive CIMT demonstrated larger improvements than the distributed CIMT did on quality of use of the more-affected hand, as rated by parents on the PMAL-R at week 8.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The 2 dosing schedules of CIMT had similar effectiveness for children with unilateral CP. The intensive CIMT yielded additional improvement on parent rated motor quality of the more-affected hand at 8 weeks after the initiation of treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration:<\/jats:title>\n                    <jats:p>ClinicalTrials.gov (ID: NCT03128385)<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15459683231162330","type":"journal-article","created":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T01:31:15Z","timestamp":1680053475000},"page":"109-118","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Effects of Intensive Versus Distributed Constraint-Induced Movement Therapy for Children With Unilateral Cerebral Palsy: A Quasi-Randomized Trial"],"prefix":"10.1177","volume":"37","author":[{"given":"Tien-Ni","family":"Wang","sequence":"first","affiliation":[{"name":"School of Occupational Therapy, College of Medicine, National Taiwan University, Taipei"},{"name":"Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai-Jie","family":"Liang","sequence":"additional","affiliation":[{"name":"School of Occupational Therapy, College of Medicine, National Taiwan University, Taipei"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Chia","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Taipei Hospital, Ministry of Health and Welfare, New Taipei City"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeng-Yi","family":"Shieh","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5972-2778","authenticated-orcid":false,"given":"Hao-Ling","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Occupational Therapy, College of Medicine, National Taiwan University, Taipei"},{"name":"Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,3,28]]},"reference":[{"key":"bibr1-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0191724"},{"key":"bibr2-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-67858-0_3"},{"key":"bibr3-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-2768"},{"key":"bibr4-15459683231162330","doi-asserted-by":"publisher","DOI":"10.3109\/09638288.2011.650314"},{"key":"bibr5-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1017\/S0012162206001551"},{"key":"bibr6-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.15055"},{"key":"bibr7-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-020-1022-z"},{"key":"bibr8-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/pzx107"},{"key":"bibr9-15459683231162330","volume":"4","author":"Hoare BJ","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr10-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1080\/16501960310010124"},{"key":"bibr11-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.12273"},{"key":"bibr12-15459683231162330","author":"Gordon AM","year":"2012","journal-title":"Physical Therapy for Children"},{"key":"bibr13-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1177\/0269215514544982"},{"key":"bibr14-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1080\/01942638.2018.1484407"},{"key":"bibr15-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2004.10.008"},{"key":"bibr16-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1016\/j.rehab.2017.10.004"},{"key":"bibr17-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1177\/0883073814533150"},{"key":"bibr18-15459683231162330","doi-asserted-by":"publisher","DOI":"10.3109\/17518420903386161"},{"key":"bibr19-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2011.05.024"},{"key":"bibr20-15459683231162330","doi-asserted-by":"publisher","DOI":"10.3233\/PRM-2012-0206"},{"key":"bibr21-15459683231162330","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2020.00557"},{"key":"bibr22-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1080\/01942638.2017.1407014"},{"key":"bibr23-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1111\/1440-1630.12666"},{"key":"bibr24-15459683231162330","volume-title":"International Classification of Functioning, Disability, and Health: Children & Youth Version: ICF-CY","author":"World Health Organization","year":"2007"},{"key":"bibr25-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1177\/1545968309359767"},{"key":"bibr26-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2015.06.013"},{"key":"bibr27-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g1687"},{"key":"bibr28-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.12391"},{"key":"bibr29-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1177\/000841748505200505"},{"key":"bibr30-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1037\/a0028516"},{"key":"bibr31-15459683231162330","volume-title":"BOT2: Bruininks-Oseretsky Test of Motor Proficiency","author":"Bruininks RH","year":"2005"},{"key":"bibr32-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000138423.77640.37"},{"key":"bibr33-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2001.tb01615.x"},{"key":"bibr34-15459683231162330","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2013.00863"},{"key":"bibr35-15459683231162330","doi-asserted-by":"publisher","DOI":"10.4324\/9781410606266"},{"key":"bibr36-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2017.01.024"},{"key":"bibr37-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.14184"},{"key":"bibr38-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2011.10.003"},{"key":"bibr39-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1017\/S0012162206001162"},{"key":"bibr40-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-9-44"},{"key":"bibr41-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2011.01.023"},{"key":"bibr42-15459683231162330","doi-asserted-by":"publisher","DOI":"10.3109\/09638288.2011.585214"},{"key":"bibr43-15459683231162330","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2010.02.015"}],"container-title":["Neurorehabilitation and Neural Repair"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15459683231162330","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/15459683231162330","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15459683231162330","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T07:09:49Z","timestamp":1777705789000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/15459683231162330"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":43,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["10.1177\/15459683231162330"],"URL":"https:\/\/doi.org\/10.1177\/15459683231162330","relation":{},"ISSN":["1545-9683","1552-6844"],"issn-type":[{"value":"1545-9683","type":"print"},{"value":"1552-6844","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2]]}}}