{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T19:20:17Z","timestamp":1793992817799,"version":"4.8.0"},"reference-count":59,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T00:00:00Z","timestamp":1712188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Fondation pour la Recherche sur les AVC"},{"name":"Erganeo"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Neurorehabil Neural Repair"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Knowing how impaired manual dexterity and finger proprioception affect upper limb activity capacity is important for delineating targeted post-stroke interventions for upper limb recovery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To investigate whether impaired manual dexterity and finger proprioception explain variance in post-stroke activity capacity, and whether they explain more variance than conventional clinical assessments of upper limb sensorimotor impairments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Activity capacity and hand sensorimotor impairments were assessed using clinical measures in N\u2009=\u200942 late subacute\/chronic hemiparetic stroke patients. Dexterity was evaluated using the Dextrain Manipulandum to quantify accuracy of visuomotor finger force-tracking (N\u2009=\u200936), timing of rhythmic tapping (N\u2009=\u200936), and finger individuation (N\u2009=\u200924), as well as proprioception (N\u2009=\u200927). Stepwise multivariate and hierarchical linear regression models were used to identify impairments best explaining activity capacity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Dexterity and proprioceptive components significantly increased the variance explained in activity capacity: (i) Box and Block Test was best explained by baseline tonic force during force-tracking and tapping frequency (adjusted\n                      <jats:italic toggle=\"yes\">R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u2009.51); (ii) Motor Activity Log was best explained by success rate in finger individuation (adjusted\n                      <jats:italic toggle=\"yes\">R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u2009.46); (iii) Action Research Arm Test was best explained by release of finger force and proprioceptive measures (improved reaction time related to use of proprioception; adjusted\n                      <jats:italic toggle=\"yes\">R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u2009.52); and (iv) Moberg Pick-Up test was best explained by proprioceptive function (adjusted\n                      <jats:italic toggle=\"yes\">R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u2009.18). Models excluding dexterity and proprioception variables explained up to 19% less variance.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Manual dexterity and finger proprioception explain unique variance in activity capacity not captured by conventional impairment measures and should be assessed when considering the underlying causes of post-stroke activity capacity limitations.<\/jats:p>\n                    <jats:p>\n                      URL:\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.clinicaltrials.gov\">https:\/\/www.clinicaltrials.gov<\/jats:ext-link>\n                      . Unique identifier: NCT03934073.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15459683241245416","type":"journal-article","created":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T05:39:43Z","timestamp":1712209183000},"page":"373-385","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Post-Stroke Impairments of Manual Dexterity and Finger Proprioception: Their Contribution to Upper Limb Activity Capacity"],"prefix":"10.1177","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8952-6356","authenticated-orcid":false,"given":"Coralie","family":"van Ravestyn","sequence":"first","affiliation":[{"name":"Department of Neurology, Stroke Unit, CHU UCL Namur, UCLouvain, Yvoir, Belgium"},{"name":"NEUR Division, Institute of NeuroScience, UCLouvain, Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2058-6750","authenticated-orcid":false,"given":"Elo\u00efse","family":"Gerardin","sequence":"additional","affiliation":[{"name":"Department of Neurology, Stroke Unit, CHU UCL Namur, UCLouvain, Yvoir, Belgium"},{"name":"NEUR Division, Institute of NeuroScience, UCLouvain, Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxime","family":"T\u00e9r\u00e9metz","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1226, F-75014 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Hamdoun","sequence":"additional","affiliation":[{"name":"Service de M\u00e9decine Physique et de R\u00e9adaptation, GHU Paris Psychiatrie &amp; Neurosciences, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Claude","family":"Baron","sequence":"additional","affiliation":[{"name":"GHU-Paris Psychiatrie &amp; Neurosciences, FHU NeuroVasc, H\u00f4pital Sainte Anne, F-75014 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Calvet","sequence":"additional","affiliation":[{"name":"GHU-Paris Psychiatrie &amp; Neurosciences, FHU NeuroVasc, H\u00f4pital Sainte Anne, F-75014 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Vandermeeren","sequence":"additional","affiliation":[{"name":"Department of Neurology, Stroke Unit, CHU UCL Namur, UCLouvain, Yvoir, Belgium"},{"name":"NEUR Division, Institute of NeuroScience, UCLouvain, Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Turc","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1226, F-75014 Paris, France"},{"name":"GHU-Paris Psychiatrie &amp; 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