{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T08:55:42Z","timestamp":1790326542138,"version":"4.1.0"},"reference-count":48,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T00:00:00Z","timestamp":1750291200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T00:00:00Z","timestamp":1750291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Wroclaw Medical University grant","award":["SUBZ.C270.24.078"],"award-info":[{"award-number":["SUBZ.C270.24.078"]}]},{"name":"European Reseach Area Projects ERA-NET","award":["NCBiR ERA-NET-NEURON\/13\/2018"],"award-info":[{"award-number":["NCBiR ERA-NET-NEURON\/13\/2018"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Neurorehabil Neural Repair"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Assessment of sensorimotor cortex and tracts degeneration using novel diffusion tensor imaging (DTI) templates in patients with chronic spinal cord injury (SCI) and its correlation with clinical and neurophysiological findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Sex and age-matched 29 patients with chronic SCI (paraplegic: p-SCI; tetraplegic: t-SCI) and 29 healthy controls underwent neurophysiological assessment including motor evoked potentials (MEP). DTI was performed on 3\u2009T magnetic resonance imaging scanner and postprocessed using Human Motor Area and Sensorimotor Area Tract Templates. DTI parameters were compared using analysis of covariance with post hoc Scheff\u00e9 and Bonferroni corrections. Spearman\u2019s rank test was used for correlations with\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.05 considered significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Compared to controls, all SCI patients showed significantly lower fractional anisotropy (FA) in several tracts (primary motor [M1], somatosensory [S1], pre-supplementary motor area [preSMA], and dorsal premotor [PMd]) and cortices (M1, pre-SMA, and S1). There were no differences in DTI parameters between p-SCI and t-SCI or p-SCI and controls. Compared to controls, t-SCI showed significantly decreased FA within M1 and S1 tracts. In t-SCI higher motor scores were associated with higher FA from ventral premotor area (PMv) tracts and cortex; higher sensory scores were associated with higher FA from S1 tracts. Positive correlations were found between MEP amplitudes from rectus femoris muscles and FA for M1, PMd, PMv, pre-SMA, SMA tracts, and PMv cortex.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>DTI shows remote degeneration of sensorimotor cortex and supraspinal tracts in SCI correlating with several clinical motor and sensory scores, and MEP parameters. DTI metrics have the potential to become biomarkers of remote degeneration.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15459683251345434","type":"journal-article","created":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T23:00:47Z","timestamp":1750374047000},"page":"701-714","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Diffusion Tensor Imaging Findings in Cerebral Sensorimotor Areas in Patients After Spinal Cord Injury Correlate With Neurophysiological Deficits"],"prefix":"10.1177","volume":"39","author":[{"given":"Anna","family":"Zimny","sequence":"first","affiliation":[{"name":"Department of General and Interventional Radiology and Neuroradiology, Wroclaw Medical University, Wroclaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Przemys\u0142aw","family":"Podg\u00f3rski","sequence":"additional","affiliation":[{"name":"Department of General and Interventional Radiology and Neuroradiology, Wroclaw Medical University, Wroclaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7240-479X","authenticated-orcid":false,"given":"Weronika","family":"Machaj","sequence":"additional","affiliation":[{"name":"Department of General and Interventional Radiology and Neuroradiology, Wroclaw Medical University, Wroclaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Fortuna","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Wroclaw Medical University, Wroclaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8671-0497","authenticated-orcid":false,"given":"Juliusz","family":"Huber","sequence":"additional","affiliation":[{"name":"Department of Pathophysiology of Locomotor Organs, Poznan University of Medical Sciences, Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Bobek-Billewicz","sequence":"additional","affiliation":[{"name":"Department of Radiology, National Institute of Oncology, Gliwice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawe\u0142","family":"Tabakow","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Wroclaw Medical University, Wroclaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,6,19]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2017.18"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.00282"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(13)70146-7"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.3390\/app11209764"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2005.12.010"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(19)30138-3"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2018.00092"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-34328-z"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-57706-7"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41393-019-0309-x"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.24964"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.4103\/1673-5374.344839"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2013.164"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.23619"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2019.00011"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.11-03-00667.1991"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1177\/1073858414537381"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2006.02.004"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhx066"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines11102602"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines11041035"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10132975"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmr.2014.04.001"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-61737-992-5_6"},{"key":"e_1_3_2_26_2","first-page":"18","volume-title":"Proceedings of the 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine","author":"Leemans A","year":"2009","unstructured":"Leemans A, Jeurissen B, Sijbers J, Jones DK. 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