{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T16:41:15Z","timestamp":1781541675918,"version":"3.54.5"},"reference-count":56,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,12,27]],"date-time":"2025-12-27T00:00:00Z","timestamp":1766793600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000090","name":"Congressionally Directed Medical Research Programs","doi-asserted-by":"publisher","award":["SCI Clinical Trials"],"award-info":[{"award-number":["SCI Clinical Trials"]}],"id":[{"id":"10.13039\/100000090","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Department of Defense Clinical Trials","award":["W81XWH-18-1-0796"],"award-info":[{"award-number":["W81XWH-18-1-0796"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Neurorehabil Neural Repair"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The amount of walking practice may influence locomotor recovery in individuals with motor incomplete spinal cord injury (iSCI), although the contributions of exercise intensity are not well established.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The purpose of this blinded-assessor randomized trial was to determine the contributions of exercise intensity on locomotor outcomes in individuals &gt;6\u2009months following iSCI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Ambulatory individuals post-iSCI with walking speeds &lt;1.0\u2009m\/s were assigned to \u226430 sessions of either high-intensity training (HIT: &gt;70% heart rate [HR] reserve or ratings of perceived exertion [RPE] \u226515) or low-intensity training (LIT; &lt;40% HR reserve; RPE \u226413). Assessments were performed at baseline, post-training, and at 3-month follow-up evaluation, with primary outcomes of fastest walking speeds over 10\u2009m and during graded treadmill exercise tests, and secondary clinical and metabolic outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 65 participants screened, 53 were randomized to HIT (n\u2009=\u200928) or LIT (n\u2009=\u200925) and completed 1489\/1590 (94%) planned training sessions. Peak HRs and RPEs were greater during HIT (both\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.001). Changes in fastest gait speeds overground were not significantly different between HIT and LIT when using Bonferroni corrections (\u03b1\u2009=\u2009.025; mean post-training differences: 0.11\u2009m\/s [95% CI: 0.04-0.17\u2009m\/s],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.031), although gains in peak treadmill speed were significant (mean differences: 0.25\u2009m\/s [0.15-0.34\u2009m\/s],\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u2009.001]. Secondary outcomes of 6-minute walk test (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.002) and combined measures of peak metabolic capacity and efficiency (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.001) were also greater with HIT.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Greater gains in peak treadmill speed, 6-minute walk, and selected metabolic outcomes were observed with HIT versus LIT in individuals with iSCI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/clinicaltrials.gov\/\">https:\/\/clinicaltrials.gov\/<\/jats:ext-link>\n                      ; Unique Identifier: NCT03714997.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15459683251399158","type":"journal-article","created":{"date-parts":[[2025,12,27]],"date-time":"2025-12-27T08:17:27Z","timestamp":1766823447000},"page":"49-60","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Higher Intensity Walking Training in Individuals With Chronic Motor Incomplete Spinal Cord Injury: A Randomized Clinical Trial"],"prefix":"10.1177","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3147-3818","authenticated-orcid":false,"given":"T. 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