{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T07:25:14Z","timestamp":1787383514736,"version":"build-2736575974"},"reference-count":48,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T00:00:00Z","timestamp":1778198400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100020950","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["NSTC 112-2314-B-002-116-MY3"],"award-info":[{"award-number":["NSTC 112-2314-B-002-116-MY3"]}],"id":[{"id":"10.13039\/501100020950","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Neurorehabil Neural Repair"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Dual-task walking poses substantial challenges for individuals with Parkinson\u2019s disease (PD), particularly those with freezing of gait (FOG), as dual-task interference increases fall risk and limits functional mobility.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To investigate dual-task interference at both the behavioral and neural levels in PD individuals with FOG (PDFOG+) and those without FOG (PDFOG\u2212) during dual-task walking involving a demanding manual task.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Seventeen PDFOG\u2212 and 17 PDFOG+ participated in this study. Gait performance, manual-task performance, and scalp electroencephalograph (EEG) were recorded in single-task condition and dual-task walking while performing a high attentional-load manual task (an interlocking ring task). The primary behavioral outcomes were dual-task costs (DTC) of gait velocity and ring performance, representing locomotor interference and manual-task interference, respectively. The primary neural outcomes focused on theta-band EEG measures, including regional theta power and inter-regional theta connectivity, given their established role in attentional control during dual-task walking in PDFOG+.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Compared with PDFOG\u2212, PDFOG+ exhibited significantly less DTC of gait velocity and greater DTC of ring performance. At the neural level, PDFOG+ demonstrated attenuated task-dependent modulations of increased theta-band power and decreased theta-band connectivity relative to PDFOG\u2212.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>PDFOG+ exhibited an atypical pattern of dual-task interference characterized by preserved gait velocity at the expense of concurrent manual-task performance, together with diminished theta-band attentional modulation. These findings suggest limited flexibility in attentional resource allocation in PDFOG+ and highlight theta-band neural dynamics as a key mechanism underlying maladaptive task-task regulation during walking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration:<\/jats:title>\n                    <jats:p>National Taiwan University Hospital Research Ethics Committee: No. NCT03298503.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15459683261448466","type":"journal-article","created":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T11:23:31Z","timestamp":1778239411000},"page":"631-642","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Atypical Dual-Task Cost and Reduced Attentional Neural Modulation in Parkinson\u2019s Disease With Freezing of Gait"],"prefix":"10.1177","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5168-2940","authenticated-orcid":false,"given":"Ing-Shiou","family":"Hwang","sequence":"first","affiliation":[{"name":"Department of Physical Therapy, College of Medicine, National Cheng Kung University, Tainan, Taiwan"},{"name":"Institute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-An","family":"Chen","sequence":"additional","affiliation":[{"name":"Division of Physical Therapy, Department of Rehabilitation, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruey-Meei","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6946-2105","authenticated-orcid":false,"given":"Cheng-Ya","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, College of Medicine, National Cheng Kung University, Tainan, Taiwan"},{"name":"School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,8]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0003-9993(00)90230-2"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/1545968316650426"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/1545968320924430"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11357-022-00606-3"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-023-11610-8"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.3233\/JPD-230245"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/82.9.888"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2018.12.012"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1159\/000070402"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1518\/001872008X288394"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2016.03.007"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(11)70143-0"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/1545968320969940"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2014-308840"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1177\/089198879901100403"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23327"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.3233\/JPD-230063"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2017.05.006"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2013.09.006"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2022.01.128"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2016.05.031"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2020.568703"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awr315"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnsys.2022.995375"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2016.09.014"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2024.106557"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2009.07.108"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/8032180"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11357-022-00516-4"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2007.04.027"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.20346"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2025.04.012"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2010.06.041"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20998"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2015.02.049"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00744.2012"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.29889"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00409.2005"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1397-20.2020"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1111\/ejn.14959"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-019-05550-x"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1037\/\/0003-066x.57.9.705"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0167-8760(96)00066-9"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2010.02.015"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2019.12.399"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-021-02544-w"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1111\/psyp.14647"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2022.758452"}],"container-title":["Neurorehabilitation and Neural Repair"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15459683261448466","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/15459683261448466","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15459683261448466","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T06:57:40Z","timestamp":1787381860000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/15459683261448466"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,8]]},"references-count":48,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1177\/15459683261448466"],"URL":"https:\/\/doi.org\/10.1177\/15459683261448466","relation":{},"ISSN":["1545-9683","1552-6844"],"issn-type":[{"value":"1545-9683","type":"print"},{"value":"1552-6844","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,8]]}}}