{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T11:15:49Z","timestamp":1788347749347,"version":"build-2803163510"},"reference-count":61,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T00:00:00Z","timestamp":1246406400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin EEG Neurosci"],"published-print":{"date-parts":[[2009,7]]},"abstract":"<jats:p>Conventional EEG and quantitative EEG visual stimuli (close-open eyes) reactivity analysis have shown their usefulness in clinical practice; however studies at the level of EEG generators are limited. The focus of the study was visual reactivity of cortical resources in healthy subjects and in a stroke patient.<\/jats:p>\n                  <jats:p>The 64 channel EEG and T1 magnetic resonance imaging (MRI) studies were obtained from 32 healthy subjects and a middle cerebral artery stroke patient. Low Resolution Electromagnetic Tomography (LORETA) was used to estimate EEG sources for both close eyes (CE) vs. open eyes (OE) conditions using individual MRI. The t-test was performed between source spectra of the two conditions. Thresholds for statistically significant t values were estimated by the local false discovery rate (lfdr) method. The Z transform was used to quantify the differences in cortical reactivity between the patient and healthy subjects.<\/jats:p>\n                  <jats:p>Closed-open eyes alpha reactivity sources were found mainly in posterior regions (occipito-parietal zones), extended in some cases to anterior and thalamic regions. Significant cortical reactivity sources were found in frequencies different from alpha (lower t-values). Significant changes at EEG reactivity sources were evident in the damaged brain hemisphere. Reactivity changes were also found in the \u201chealthy\u201d hemisphere when compared with the normal population.<\/jats:p>\n                  <jats:p>In conclusion, our study of brain sources of EEG alpha reactivity provides information that is not evident in the usual topographic analysis.<\/jats:p>","DOI":"10.1177\/155005940904000306","type":"journal-article","created":{"date-parts":[[2012,2,22]],"date-time":"2012-02-22T16:03:18Z","timestamp":1329926598000},"page":"150-156","source":"Crossref","is-referenced-by-count":20,"title":["Source Analysis of Alpha Rhythm Reactivity Using LORETA Imaging with 64-Channel EEG and Individual MRI"],"prefix":"10.1177","volume":"40","author":[{"given":"E.R.","family":"Cuspineda","sequence":"first","affiliation":[{"name":"Havana Institute of Neurology and Neurosurgery, Havana City, Cuba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Machado","sequence":"additional","affiliation":[{"name":"Havana Institute of Neurology and Neurosurgery, Havana City, Cuba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Virues","sequence":"additional","affiliation":[{"name":"Cuban Neuroscience Center, Havana City, Cuba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Mart\u00ednez-Montes","sequence":"additional","affiliation":[{"name":"Cuban Neuroscience Center, Havana City, Cuba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Ojeda","sequence":"additional","affiliation":[{"name":"Cuban Neuroscience Center, Havana City, Cuba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. 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