{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T17:48:38Z","timestamp":1777571318918,"version":"3.51.4"},"reference-count":32,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2014,3,10]],"date-time":"2014-03-10T00:00:00Z","timestamp":1394409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin EEG Neurosci"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:p>Periventricular leukomalacia (PVL) is characterized by necrosis of the cerebral white matter in the dorsolateral portions of the lateral ventricles. PVL causes motor, sensory, and cognitive deficits. The aim of this study was to analyze the conduction characteristics of the visual pathway in infants with diffuse PVL using visual evoked potentials (VEPs). We studied 11 healthy infants (mean age 3.3 \u00b1 1.3 months) and 17 with diffuse PVL (mean age 2.9 \u00b1 0.8 months and mean gestational age 31.9 \u00b1 3.1 weeks). The N75, P100, and N135 wave latencies; the interwave N75-P100 and P100-N135 latencies; and the N75-P100 and P100-N135 amplitudes were measured in the occipital leads. VEPs were recorded during binocular stimulation at an angle of 120\u2032 from the Fz-Oz lead. Healthy children had mean N75, P100, and N135 wave latencies of 84.4 \u00b1 5.8, 143.4 \u00b1 30.6 and 222.9 \u00b1 40.4 ms, respectively. The mean interwave N75-P100 and P100-N135 latencies were 59.0 \u00b1 28.6 and 79.5 \u00b1 13.6 ms, respectively. Compared with the healthy group, infants with PVL had longer N75 and N135 latencies at 92.3 \u00b1 15.3 ( P = .05) and 265.0 ms \u00b1 60.3 ( P = .05), respectively. The interwave latency P100-N135 (105.5 \u00b1 29.1 ms; P = .017) was longer in children with PVL than in healthy infants. Infants with diffuse PVL had mild alterations in their N75, P100 and, particularly, their N135 latencies. These increases in P100-N135 interwave latencies could be because of damage to the geniculocortical pathways and V2-V3 networks.<\/jats:p>","DOI":"10.1177\/1550059413515655","type":"journal-article","created":{"date-parts":[[2014,3,10]],"date-time":"2014-03-10T22:30:32Z","timestamp":1394490632000},"page":"269-273","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Visual Evoked Potentials in Infants With Diffuse Periventricular Leukomalacia"],"prefix":"10.1177","volume":"45","author":[{"given":"Cintli Carolina","family":"Carbajal-Valenzuela","sequence":"first","affiliation":[{"name":"Unidad de Investigaci\u00f3n en Neurodesarrollo \u201cDr. Augusto Fern\u00e1ndez Guardiola\u201d, Instituto de Neurobiolog\u00eda, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM), Juriquilla, Quer\u00e9taro, 76230, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Efra\u00edn","family":"Santiago-Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Unidad de Investigaci\u00f3n en Neurodesarrollo \u201cDr. Augusto Fern\u00e1ndez Guardiola\u201d, Instituto de Neurobiolog\u00eda, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM), Juriquilla, Quer\u00e9taro, 76230, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thal\u00eda","family":"Harmony","sequence":"additional","affiliation":[{"name":"Unidad de Investigaci\u00f3n en Neurodesarrollo \u201cDr. Augusto Fern\u00e1ndez Guardiola\u201d, Instituto de Neurobiolog\u00eda, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM), Juriquilla, Quer\u00e9taro, 76230, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Fern\u00e1ndez-Bouzas","sequence":"additional","affiliation":[{"name":"Unidad de Investigaci\u00f3n en Neurodesarrollo \u201cDr. Augusto 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