{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:39:46Z","timestamp":1787495986938,"version":"build-2736575974"},"reference-count":14,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin EEG Neurosci"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:p>We report on an 18-month-old boy with unilateral left eye blinking as a single ictal manifestation without facial twitching. The clinical onset of this phenomenon was first recorded (as an occasional event) at age 3 months, and it was overlooked. By age 6 months, the child\u2019s blinking increased to almost daily occurrence in clusters: during blinking the infant showed intact awareness and occasional jerks in the upper limbs and right leg. A video-electroencephalography (video-EEG) documented clinical correlation with a focal pattern arising from the left occipital region, and brain magnetic resonance imaging (MRI) revealed severe brain damage, consisting in poroencephalic hollows and increased spaces in the convexities involving a large area of the left cerebral hemisphere. The boy was prescribed sodium valproate (30 mg\/kg\/d), resulting in drastic reduction of his clinical seizures. Follow-up to his current age documented good general status, with persistent partial right hemilateral seizures. The blinking progressively disappeared, and is no longer recorded. The pathogenic hypotheses of the unilateral ictal blinking include involvement of the ipsilateral cerebral hemisphere and\/or the cerebellar pathways. Review of previous reports of unilateral eye blinking, arising from the ictal ipsilateral brain, revealed that different damaged regions may give rise to blinking ictal phenomena, likely via the trigeminal fibres innervating the subdural intracranial structures and the pial vessels in the ipsilateral affected brain. The eye blinking in the present child represents a further example of an ictal phenomenon, which is predictive of the damaged brain region.<\/jats:p>","DOI":"10.1177\/1550059414533111","type":"journal-article","created":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T21:26:19Z","timestamp":1409606779000},"page":"243-246","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":46,"title":["Unilateral Eye Blinking Arising From the Ictal Ipsilateral Occipital Area"],"prefix":"10.1177","volume":"47","author":[{"given":"Raffaele","family":"Falsaperla","sequence":"first","affiliation":[{"name":"Unit of Pediatrics and Pediatric Emergency \u201cCostanza Gravina\u201d, University Hospital \u201cVittorio Emanuele, Policlinic\u201d, Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Perciavalle","sequence":"additional","affiliation":[{"name":"Department of Educational Sciences, University of Catania, Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piero","family":"Pavone","sequence":"additional","affiliation":[{"name":"Unit of Pediatrics and Pediatric Emergency \u201cCostanza Gravina\u201d, University Hospital \u201cVittorio Emanuele, Policlinic\u201d, Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea Domenico","family":"Pratic\u00f2","sequence":"additional","affiliation":[{"name":"Pediatric Clinic, University of Catania, Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Elia","sequence":"additional","affiliation":[{"name":"IRCCS Oasi Maria Santissima, Troina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martino","family":"Ruggieri","sequence":"additional","affiliation":[{"name":"Department of Educational Sciences, University of Catania, Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Caraballo","sequence":"additional","affiliation":[{"name":"Department of Neurology, Juan P. Garrahan Pediatric Hospital, Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pasquale","family":"Striano","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, G. Gaslini Institute, Genoa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,9,1]]},"reference":[{"key":"bibr1-1550059414533111","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2002.97.1.0190"},{"key":"bibr2-1550059414533111","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.12.2519"},{"key":"bibr3-1550059414533111","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1994.tb02552.x"},{"key":"bibr4-1550059414533111","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.38.7.1048"},{"key":"bibr5-1550059414533111","first-page":"15","volume":"35","author":"Bleasel A","year":"1994","journal-title":"Epilepsia"},{"key":"bibr6-1550059414533111","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.46.1.45"},{"key":"bibr7-1550059414533111","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.35.12.1760"},{"key":"bibr8-1550059414533111","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1684\/j.1950-6945.1999.tb00320.x","volume":"1","author":"Henkel A","year":"1999","journal-title":"Epileptic Disord"},{"key":"bibr9-1550059414533111","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1684\/epd.2007.0130","volume":"9","author":"Pestana EM","year":"2007","journal-title":"Epileptic Disord"},{"key":"bibr10-1550059414533111","doi-asserted-by":"publisher","DOI":"10.1007\/BF01400654"},{"key":"bibr11-1550059414533111","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.06-08-02200.1986"},{"key":"bibr12-1550059414533111","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awg011"},{"key":"bibr13-1550059414533111","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.10056"},{"key":"bibr14-1550059414533111","first-page":"533","volume-title":"Advances in Epileptology. 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