{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T19:17:08Z","timestamp":1788635828786,"version":"build-2803163510"},"reference-count":39,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2019,10,4]],"date-time":"2019-10-04T00:00:00Z","timestamp":1570147200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin EEG Neurosci"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:p>Aim. In this study we assessed the predictive power of quantitative EEG (qEEG) for the treatment response to right frontal transcranial magnetic stimulation (TMS) in obsessive compulsive disorder (OCD) using a machine learning approach. Method. The study included 50 OCD patients (35 responsive to TMS, 15 nonresponsive) who were treated with right frontal low frequency stimulation and identified retrospectively from Uskudar Unversity, NPIstanbul Brain Hospital outpatient clinic. All patients were diagnosed with OCD according to the DSM-IV-TR and DSM-5 criteria. We first extracted pretreatment band powers for patients. To explore the prediction accuracy of pretreatment EEG, we employed machine learning methods using an artificial neural network model. Results. Among 4 EEG bands, theta power successfully discriminated responsive from nonresponsive patients. Responsive patients had more theta powers for all electrodes as compared to nonresponsive patients. Discussion. qEEG could be helpful before deciding about treatment strategy in OCD. The limitations of our study are moderate sample size and limited number of nonresponsive patients and that treatment response was defined by clinicians and not by using a formal symptom measurement scale. Future studies with larger samples and prospective design would show the role of qEEG in predicting TMS response better.<\/jats:p>","DOI":"10.1177\/1550059419879569","type":"journal-article","created":{"date-parts":[[2019,10,4]],"date-time":"2019-10-04T08:04:30Z","timestamp":1570176270000},"page":"139-145","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":25,"title":["Use of EEG for Predicting Treatment Response to Transcranial Magnetic Stimulation in Obsessive Compulsive Disorder"],"prefix":"10.1177","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0511-2867","authenticated-orcid":false,"given":"Sinem Zeynep","family":"Metin","sequence":"first","affiliation":[{"name":"Department of Psychology, Uskudar University, Istanbul, Turkey"},{"name":"Department of Psychiatry, NPIstanbul Brain Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tug\u00e7e","family":"Balli Altuglu","sequence":"additional","affiliation":[{"name":"Faculty of Engineering and Natural Sciences, Department of Computer Engineering, Uskudar University, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baris","family":"Metin","sequence":"additional","affiliation":[{"name":"Department of Psychology, Uskudar University, Istanbul, Turkey"},{"name":"Department of Neurology, NPIstanbul Brain Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8438-6542","authenticated-orcid":false,"given":"Turker Tekin","family":"Erguzel","sequence":"additional","affiliation":[{"name":"Faculty of Engineering and Natural Sciences, Department of Computer Engineering, Uskudar University, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selin","family":"Yigit","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Uskudar University, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1500-6555","authenticated-orcid":false,"given":"Mehmet Kemal","family":"Ar\u0131kan","sequence":"additional","affiliation":[{"name":"Department of Psychology, Uskudar University, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kasif Nevzat","family":"Tarhan","sequence":"additional","affiliation":[{"name":"Department of Psychology, Uskudar University, Istanbul, Turkey"},{"name":"Department of Psychiatry, NPIstanbul Brain Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,10,4]]},"reference":[{"key":"bibr1-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"bibr2-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2008.94"},{"key":"bibr3-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1002\/da.20506"},{"key":"bibr4-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1038\/sj.mp.4001823"},{"key":"bibr5-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.2200"},{"key":"bibr6-1550059419879569","doi-asserted-by":"publisher","DOI":"10.12740\/PP\/27018"},{"key":"bibr7-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2012.06.001"},{"key":"bibr8-1550059419879569","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.08m04872gre"},{"key":"bibr9-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2011.04.010"},{"key":"bibr10-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.154.6.867"},{"key":"bibr11-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1996.01830020023004"},{"key":"bibr12-1550059419879569","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v62n1211"},{"key":"bibr13-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.158.7.1143"},{"key":"bibr14-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1016\/j.janxdis.2010.03.011"},{"key":"bibr15-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1177\/155005940303400205"},{"key":"bibr16-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1017\/S1461145705005584"},{"key":"bibr17-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2006.00889.x"},{"key":"bibr18-1550059419879569","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2015.01993"},{"key":"bibr19-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2017.07.406"},{"key":"bibr20-1550059419879569","first-page":"942","volume-title":"Proceedings of IEEE International Conference on Neural Networks 1995 (ICNN\u201995)","volume":"1995","author":"Kennedy J"},{"key":"bibr21-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemolab.2015.08.020"},{"key":"bibr22-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1007\/s00521-015-1959-z"},{"key":"bibr23-1550059419879569","volume-title":"Neural Networks and Learning Machines","author":"Haykin S.","year":"2008","edition":"3"},{"key":"bibr24-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1016\/j.eswa.2004.12.027"},{"key":"bibr25-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1109\/TITB.2006.884369"},{"key":"bibr26-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1007\/s10916-008-9145-9"},{"key":"bibr27-1550059419879569","doi-asserted-by":"publisher","DOI":"10.4306\/pi.2015.12.1.61"},{"key":"bibr28-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2017.09.017"},{"key":"bibr29-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1016\/S0004-3702(97)00063-5"},{"key":"bibr30-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1016\/j.compeleceng.2013.11.024"},{"key":"bibr31-1550059419879569","volume-title":"Machine Learning","author":"Mitchell T.","year":"1997"},{"key":"bibr33-1550059419879569","volume-title":"L\u2019optimisation par Essaim Particulaire: Versions Parame \u2019triques et Adaptatives","author":"Clerc M.","year":"2005"},{"key":"bibr34-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1504\/IJICA.2007.013400"},{"key":"bibr35-1550059419879569","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1007\/978-3-642-17563-3_73","volume-title":"Swarm, Evolutionary, and Memetic Computing","volume":"6466","author":"Killani R"},{"key":"bibr36-1550059419879569","first-page":"193","volume-title":"Pattern Recognition","author":"Nguyen GH","year":"2009"},{"key":"bibr37-1550059419879569","first-page":"83","volume":"44","author":"Albert U","year":"2002","journal-title":"Panminerva Med"},{"key":"bibr38-1550059419879569","doi-asserted-by":"crossref","first-page":"S66","DOI":"10.1590\/S1516-44462006005000059","volume":"29","author":"Ferr\u00e3o YA","year":"2007","journal-title":"Braz J Psychiatry"},{"key":"bibr39-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpsc.2018.01.008"},{"key":"bibr40-1550059419879569","doi-asserted-by":"publisher","DOI":"10.1097\/01.wnp.0000221363.12503.78"}],"container-title":["Clinical EEG and Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1550059419879569","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1550059419879569","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1550059419879569","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:13:41Z","timestamp":1777403621000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1177\/1550059419879569"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,4]]},"references-count":39,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["10.1177\/1550059419879569"],"URL":"https:\/\/doi.org\/10.1177\/1550059419879569","relation":{},"ISSN":["1550-0594","2169-5202"],"issn-type":[{"value":"1550-0594","type":"print"},{"value":"2169-5202","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,4]]}}}