{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T00:23:08Z","timestamp":1781742188043,"version":"3.54.5"},"reference-count":14,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T00:00:00Z","timestamp":1589500800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin EEG Neurosci"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>Frontal intermittent rhythmic delta activity (FIRDA), rhythmic slow wave pattern lasting several seconds over the anterior leads of electroencephalography (EEG), has been reported in a wide variety of clinical conditions. We investigated the clinical significance of FIRDA without structural brain lesions. We reviewed 7689 EEGs between October 2017 and September 2019 at a university hospital. Patients (age &gt;18 years) who were confirmed to have \u201cnonsignificant neuroimaging\u201d were examined. Clinical data were retrospectively collected, and the estimated cause was carefully decided. We found 83 FIRDA among 7689 EEGs (1.08%). After patients with any structural lesion identified on neuroimaging were excluded, 37 FIRDAs were reviewed. There were 20 (51.35%) patients of metabolic encephalopathy. Six patients showed FIRDA due to neurodegenerative disease (16.21%). In addition, we found 6 (16.21%) of neurodegenerative disease and 5 (13.51%) of hypoxic encephalopathy (cardiac arrest). Four (16.21%) patients were related to systemic infection (10.81%), whereas 2 were related to encephalitis (5.40%). We demonstrated several potential etiologies, including metabolic encephalopathy, neurodegenerative disease, hypoxic encephalopathy, and infections, which should be considered in the case of FIRDA without structural brain lesions.<\/jats:p>","DOI":"10.1177\/1550059420922741","type":"journal-article","created":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T13:38:53Z","timestamp":1589549933000},"page":"69-73","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":24,"title":["Clinical Correlates of Frontal Intermittent Rhythmic Delta Activity Without Structural Brain Lesion"],"prefix":"10.1177","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7124-0736","authenticated-orcid":false,"given":"Keun Tae","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Neurology, Keimyung University School of Medicine, Daegu, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young-Nam","family":"Roh","sequence":"additional","affiliation":[{"name":"Department of Surgery, Keimyung University Dongsan Medical Center, Daegu, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan Hee","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Cheon","family":"Jeon","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Keimyung University Dongsan Medical Center, Daegu, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,5,15]]},"reference":[{"key":"bibr1-1550059420922741","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.8.3-4.65"},{"key":"bibr2-1550059420922741","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(82)90161-4"},{"key":"bibr3-1550059420922741","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(59)90113-0"},{"key":"bibr4-1550059420922741","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(79)90200-1"},{"issue":"4","key":"bibr5-1550059420922741","first-page":"168","author":"Jasper H","year":"1955","journal-title":"Electroencephalogr Clin Neurophysiol Suppl"},{"key":"bibr6-1550059420922741","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2010.06.005"},{"key":"bibr7-1550059420922741","doi-asserted-by":"publisher","DOI":"10.1097\/00004691-200212000-00006"},{"key":"bibr8-1550059420922741","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2014.11.021"},{"key":"bibr9-1550059420922741","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2007.125385"},{"key":"bibr10-1550059420922741","doi-asserted-by":"publisher","DOI":"10.1159\/000330011"},{"key":"bibr11-1550059420922741","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-012-6766-1"},{"key":"bibr12-1550059420922741","doi-asserted-by":"publisher","DOI":"10.1177\/1550059416688108"},{"key":"bibr13-1550059420922741","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.27.4.326"},{"key":"bibr14-1550059420922741","doi-asserted-by":"publisher","DOI":"10.1177\/155005948301400307"}],"container-title":["Clinical EEG and Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1550059420922741","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1550059420922741","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1550059420922741","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:13:49Z","timestamp":1777403629000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1550059420922741"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,15]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1177\/1550059420922741"],"URL":"https:\/\/doi.org\/10.1177\/1550059420922741","relation":{},"ISSN":["1550-0594","2169-5202"],"issn-type":[{"value":"1550-0594","type":"print"},{"value":"2169-5202","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,15]]}}}