{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T17:55:28Z","timestamp":1777571728237,"version":"3.51.4"},"reference-count":54,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2021,7,13]],"date-time":"2021-07-13T00:00:00Z","timestamp":1626134400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100005006","name":"Asan Institute for Life Sciences, Asan Medical Center","doi-asserted-by":"publisher","award":["2019IP0852, 2018IE7038, 2019IE7038, 2020IE0004, 20"],"award-info":[{"award-number":["2019IP0852, 2018IE7038, 2019IE7038, 2020IE0004, 20"]}],"id":[{"id":"10.13039\/501100005006","id-type":"DOI","asserted-by":"publisher"}]},{"name":"the Korea government","award":["2018013748"],"award-info":[{"award-number":["2018013748"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin EEG Neurosci"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:p>\n                    <jats:italic toggle=\"yes\">Background and Purpose.<\/jats:italic>\n                    Although acute meningitis and encephalitis are known to cause cognitive dysfunction, the prognostic values of neuropsychological and neurophysiological tests in predicting clinical outcomes are seldom studied. We investigated specific neurocognitive dysfunction and event-related potentials (ERPs), which can predict functional outcomes in patients with acute meningitis and encephalitis.\n                    <jats:italic toggle=\"yes\">Methods<\/jats:italic>\n                    . We enrolled consecutive adult patients with acute meningitis and encephalitis and performed neuropsychological tests and ERP studies using a passive auditory oddball paradigm at enrollment. Patient functional outcomes were assessed using the Glasgow Outcome Scale at 6 (GOS6) months after discharge.\n                    <jats:italic toggle=\"yes\">Results<\/jats:italic>\n                    . Twenty-two patients were included in the study. Among 21 patients who performed neuropsychological tests, Korean-Trail Making Test-Elderly's version, Part A time (TMT-A time) correlated with GOS6, which remained significant even after controlling for age. We identified a significant association between TMT-A time and P3a latency. Post-hoc analysis showed that patients with longer TMT-A time (\u226523\u2005s) tended to have longer P3a latency than those with shorter TMT-A time.\n                    <jats:italic toggle=\"yes\">Conclusions<\/jats:italic>\n                    . Decreased psychomotor speed predicted poor clinical outcomes. Because TMT-A time can be performed at the bedside in a relatively short time, this might be a useful neuropsychological biomarker to predict or monitor clinical outcomes. Furthermore, passive oddball P3a may be useful in patients with more severe disease who are unable to perform the TMT task.\n                  <\/jats:p>","DOI":"10.1177\/15500594211031137","type":"journal-article","created":{"date-parts":[[2021,7,13]],"date-time":"2021-07-13T12:05:28Z","timestamp":1626177928000},"page":"229-237","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Psychomotor Speed Predicts Outcome in Patients with Acute Meningitis and Encephalitis: A Prospective Observational Study"],"prefix":"10.1177","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5418-2522","authenticated-orcid":false,"given":"Yong Seo","family":"Koo","sequence":"first","affiliation":[{"name":"Asan Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soyeon","family":"An","sequence":"additional","affiliation":[{"name":"Asan Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3723-3305","authenticated-orcid":false,"given":"Min-Ju","family":"Kim","sequence":"additional","affiliation":[{"name":"Asan Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun-Woo","family":"Kim","sequence":"additional","affiliation":[{"name":"Pusan National University Yangsan Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang-Ahm","family":"Lee","sequence":"additional","affiliation":[{"name":"Asan Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,7,13]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30499-X"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2016.74"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2006.110023"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004150200064"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1017\/S1355617797001471"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/arclin\/acy005"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0404.2000.102002118.x"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.61.5.478"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000007601"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.21216"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13052-017-0416-2"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.25421"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1089\/neu.1998.15.573"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(74)91639-0"},{"key":"e_1_3_3_16_2","first-page":"300","article-title":"A validity study on the Korean mini-mental state examination (K-MMSE) in dementia patients","volume":"24","author":"Kang YW","year":"1997","unstructured":"Kang YW, Na DL, Hahn SH. 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