{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T17:56:01Z","timestamp":1777571761833,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2021,11,13]],"date-time":"2021-11-13T00:00:00Z","timestamp":1636761600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin EEG Neurosci"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:p>Purpose: To investigate whether hyperventilation (HV) for 5\u2005minutes increases the diagnostic yield of electroencephalography (EEG) compared to 3\u2005minutes HV and to determine whether performing HV for 5\u2005minutes is feasible and safe in children. Methods: Data were evaluated from 579 children aged less than 18 years, referred to EEG for epilepsy evaluation. Occurrence of seizures, HV induced interictal epileptiform discharges precipitation and potentiation and adverse events if any were noted during the first 3\u2005minutes and last 2\u2005minutes of HV separately. Results: 398 children (68.7%) completed 5\u2005minutes HV. Seizures were precipitated during the first 3\u2005minutes of HV in 2 children, and during the last 2\u2005minutes in one more child. Inter-ictal EEG abnormalities were precipitated in the first 3\u2005minutes of HV in 31 children, and during the last 2\u2005min in 4 more children. All 398 children completed HV during the last 2\u2005minutes successfully and no adverse events occurred during the last 2\u2005minutes of HV. Conclusion: 33.33% of seizures and 11.5% of inter-ictal EEG abnormalities triggered by HV occurred during the last 2\u2005min of HV. This finding supports the utility of prolonged hyperventilation for 5\u2005minutes. Prolonged HV for 5\u2005minutes increases the diagnostic yield of EEG in paediatric population and it is safe and feasible.<\/jats:p>","DOI":"10.1177\/15500594211058266","type":"journal-article","created":{"date-parts":[[2021,11,13]],"date-time":"2021-11-13T10:42:45Z","timestamp":1636800165000},"page":"522-525","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Diagnostic Yield of Five Minutes Compared to Three Minutes Hyperventilation During Electroencephalography in Children"],"prefix":"10.1177","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9202-7910","authenticated-orcid":false,"given":"Nivetha","family":"Vasudevan","sequence":"first","affiliation":[{"name":"Sri Ramachandra Institute of Higher Education and Research, Chennai, TN, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8774-7462","authenticated-orcid":false,"given":"Ranjith Kumar","family":"Manokaran","sequence":"additional","affiliation":[{"name":"Sri Ramachandra Institute of Higher Education and Research, Chennai, TN, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saji","family":"James","sequence":"additional","affiliation":[{"name":"Sri Ramachandra Institute of Higher Education and Research, Chennai, TN, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,11,13]]},"reference":[{"key":"bibr1-15500594211058266","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-2457(99)00125-X"},{"key":"bibr2-15500594211058266","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.55.5.616"},{"key":"bibr3-15500594211058266","doi-asserted-by":"publisher","DOI":"10.1111\/epi.12720"},{"key":"bibr4-15500594211058266","doi-asserted-by":"publisher","DOI":"10.1097\/01.wnp.0000228514.40227.12"},{"key":"bibr5-15500594211058266","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2015.06.003"},{"key":"bibr6-15500594211058266","doi-asserted-by":"publisher","DOI":"10.1097\/00004691-200604000-00002"},{"key":"bibr7-15500594211058266","unstructured":"British Society for Clinical Neurophysiology. 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