{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T11:41:02Z","timestamp":1782819662558,"version":"3.54.5"},"reference-count":59,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T00:00:00Z","timestamp":1732060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin EEG Neurosci"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:p>\n                    <jats:bold>Backgrounds:<\/jats:bold>\n                    Brain morphological biomarkers could contribute to understanding the treatment response in patients with obsessive-compulsive disorder (OCD). Multimodal neuroimaging addresses this issue by providing more comprehensive information regarding neural processes and structures.\n                    <jats:bold>Objectives.<\/jats:bold>\n                    The present study aims to investigate whether patients responsive to deep Transcranial Magnetic Stimulation (TMS) differ from non-responsive individuals in terms of electrophysiology and brain morphology. Secondly, to test whether multimodal neuroimaging is superior to unimodal neuroimaging in predicting response to deep TMS.\n                    <jats:bold>Methods.<\/jats:bold>\n                    Thirty-two OCD patients who underwent thirty sessions of deep TMS treatment were included in the study. Based on a minimum 50% reduction in Yale-Brown Obsessive Compulsive Scale (Y-BOCS) scores after treatment, patients were grouped as responders (n\u2009=\u200925) and non-responders (n\u2009=\u20097). The baseline resting state qEEG and magnetic resonance imaging (MRI) records of patients were recorded. Independent sample t-test is used to compare the groups. Then, three logistic regression model were calculated for only QEEG markers, only MRI markers, and both QEEG\/MRI markers. The predictive values of the three models were compared.\n                    <jats:bold>Results.<\/jats:bold>\n                    OCD patients who responded to deep TMS treatment had increased Alpha-2 power in the left temporal area and increased volume in the left temporal pole, entorhinal area, and parahippocampal gyrus compared to non-responders. The logistic regression model showed better prediction performance when both QEEG and MRI markers were included.\n                    <jats:bold>Conclusions.<\/jats:bold>\n                    This study addresses the gap in the literature regarding new functional and structural neuroimaging markers and highlights the superiority of multimodal neuroimaging to unimodal neuroimaging techniques in predicting treatment response.\n                  <\/jats:p>","DOI":"10.1177\/15500594241298977","type":"journal-article","created":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T03:10:27Z","timestamp":1732072227000},"page":"207-216","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Multimodal Neuroimaging in the Prediction of Deep TMS Response in OCD"],"prefix":"10.1177","volume":"56","author":[{"given":"Murat","family":"A\u015f\u0131k","sequence":"first","affiliation":[{"name":"Istanbul Medeniyet University, 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