{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T13:05:15Z","timestamp":1779541515898,"version":"3.53.1"},"reference-count":60,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T00:00:00Z","timestamp":1779321600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin EEG Neurosci"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>There is a great need in distinguishing Dementia with Lewy Body (DLB) from Alzheimer's disease (AD) and elucidating its pathophysiology. Transcranial magnetic stimulation (TMS) evoked potentials (TEPs) offer a non-invasive measure of neurophysiological alterations associated with underlying disease pathology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 39 participants were included: 12 DLB, 10 AD, and 17 age-matched healthy controls (HC). TEPs were measured in the dorsolateral prefrontal cortex (DLPFC), primary motor cortex (M1), and primary visual cortex (V1).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Global mean field potential (GMFP) TEP (130-250\u2005ms) showed a significant interaction of group and stimulation site (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u2009.0101, \u03b7p\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.175) with a significant group effect (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u2009.0071, \u03b7p\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.234), attributed to higher GMFP in DLB compared to AD and HC in response to V1 stimulation (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u2009.001,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u2009.001, respectively). TEP amplitude corresponding to P60 displayed a significant group*stimulation site interaction (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u2009.0037, \u03b7p\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.202) arising from differences in DLPFC stimulation, between DLB compared to AD (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u2009.0013) and HC (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u2009.0032). DLPFC N45 presented a significant stimulation site effect not associated to a specific group in addition to DLPFC N45 amplitude being correlated to the UPDRS-III score (r\u2009=\u20090.9,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u2009.0002). A relative higher left over right DLPFC P30 amplitude was correlated with poorer MoCA scores in AD (r\u2009=\u2009\u22120.84,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u2009.002), as indicated by others before.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>DLPFC may be a target for both diagnosis and assessment of severity of motor symptoms in DLB and cognitive impairment in AD. These results propose a promising method to non-invasively distinguish DLB from AD and monitor disease, based on DLPFC and V1 network characteristics.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15500594261452759","type":"journal-article","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T13:04:38Z","timestamp":1779368678000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Prefrontal and Occipital Network Excitability Differences in Dementia with Lewy Bodies and Alzheimer's Disease"],"prefix":"10.1177","author":[{"given":"Noa","family":"Bregman","sequence":"first","affiliation":[{"name":"Tel Aviv Sourasky Medical Center"},{"name":"Faculty of Medicine and Health Sciences, Tel Aviv University, Tel Aviv, Israel"},{"name":"Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 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