{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T14:52:45Z","timestamp":1791039165720,"version":"4.1.0"},"reference-count":60,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin EEG Neurosci"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Opioid Use Disorder (OUD) is a persistent and challenging condition often treated with Methadone Maintenance Therapy (MMT). However, additional interventions may enhance treatment outcomes. This study investigates the comparison of Low-Resolution Electromagnetic Tomography Z Score Neurofeedback (LZNFB) with Dot-Probe Cognitive Rehabilitation (DPCR) in reducing the Addiction Severity Index (ASI) in opioid addicts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this randomized controlled clinical trial with a pre-test, post-test and follow-up design, 30 men with OUD under MMT were randomly assigned into three groups: LZNFB, DPCR, and control (MMT alone). The LZNFB group underwent 20 sessions of LZNFB, while the DPCR group received 15 individual sessions over two weeks using the dot-probe task. The control group continued with MMT alone. ASI scores were assessed at baseline, post-intervention, and during follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The results indicate that both interventions showed greater numerical improvement in ASI scores, with LZNFB, particularly in improving employment and support, family\/social status, psychiatric status, and drug use sub-components.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The findings preliminarily suggest that within-group improvements were observed following LZNFB and DPCR interventions. However, given the pilot nature of this study and the lack of robust between-group interaction analysis, these results should be interpreted with caution. Further fully powered studies with sham controls are required to confirm comparative efficacy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15500594261494405","type":"journal-article","created":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T12:51:47Z","timestamp":1790772707000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["LORETA Z-Score Neurofeedback and Dot-Probe Cognitive Rehabilitation for Reducing Addiction Severity in Patients with Opioid Use Disorder Receiving Methadone Maintenance Treatment: A Pilot Randomized Controlled Trial"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7060-0341","authenticated-orcid":false,"given":"Alireza","family":"Faridi","sequence":"first","affiliation":[{"name":"Zanjan University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farhad","family":"Taremian","sequence":"additional","affiliation":[{"name":"University of Social Welfare and Rehabilitation Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roghayeh","family":"Najafi-Dehjalali","sequence":"additional","affiliation":[{"name":"Zanjan University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0051-7566","authenticated-orcid":false,"given":"Robert W","family":"Thatcher","sequence":"additional","affiliation":[{"name":"Applied Neuroscience Research Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,30]]},"reference":[{"issue":"10","key":"e_1_3_3_2_2","article-title":"Introduction to the opioid epidemic: The economic burden on the healthcare system and impact on quality of life","volume":"24","author":"Hagemeier NE","year":"2018","unstructured":"Hagemeier NE. 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