{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T14:02:04Z","timestamp":1793714524681,"version":"4.6.1"},"reference-count":27,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2011,7,7]],"date-time":"2011-07-07T00:00:00Z","timestamp":1309996800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Surg Innov"],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:p>Purpose. This multicenter randomized study was designed to compare the clinical and functional results of stapled transanal rectal resection (STARR) performed with 2 staplers (PPH-01 vs. PPH-03) in the treatment of hemorrhoidal disease associated with a large internal rectal prolapse. Methods. From a total of 937 patients, referred for hemorrhoidal disease in the 20 centers involved in the study, 425 (45.3%) with prolapsed hemorrhoids associated with a large internal rectal prolapse were randomized to undergo STARR with PPH-01 or PPH-03. Postoperative evaluation was made at 3, 6, and 12 months. Results. The incidence of bleeding at the stapled line was significantly lower in the PPH-03 group than in the PPH-01 group (58\/207 [28.0%] vs. 145\/201 [72.1%]; P &lt; .0001); the mean number of hemostatic stitches was significantly higher in the PPH-01 than in the PPH-03 group (3.2 \u00b1 0.1 vs. 1.8 \u00b1 0.8; P &lt; .0001). The mean operative time was 25.1 \u00b1 11.5 minutes in the PPH-03 group and 38.1 \u00b1 15.7 minutes in the PPH-01 group ( P &lt; .0001). No major complications occurred in either of the groups. At 12-month follow-up, the success rate in the 2 groups was 94.5% in the PPH01 group and 94.2% in the PPH03 group. Conclusion. STARR performed for the treatment of hemorrhoidal disease associated with a large rectal prolapse is a safe and effective procedure. The use of the PPH-03 stapler instead of the PPH-01 guarantees a statistically significant reduction of intraoperative bleeding and a significant decrease of the operative time.<\/jats:p>","DOI":"10.1177\/1553350611412794","type":"journal-article","created":{"date-parts":[[2011,7,8]],"date-time":"2011-07-08T10:14:30Z","timestamp":1310120070000},"page":"241-247","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":24,"title":["PPH-01 Versus PPH-03 to Perform STARR for the Treatment of Hemorrhoids Associated With Large Internal Rectal Prolapse"],"prefix":"10.1177","volume":"18","author":[{"given":"Adolfo","family":"Renzi","sequence":"first","affiliation":[{"name":"Villa delle Querce Hospital, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Brillantino","sequence":"additional","affiliation":[{"name":"Villa delle Querce Hospital, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giandomenico","family":"Di Sarno","sequence":"additional","affiliation":[{"name":"Villa delle Querce Hospital, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"D\u2019Aniello","sequence":"additional","affiliation":[{"name":"Villa delle Querce Hospital, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo","family":"Giordano","sequence":"additional","affiliation":[{"name":"S. 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Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Marino","sequence":"additional","affiliation":[{"name":"Paolo Colombo Hospital, Velletri, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"Goglia","sequence":"additional","affiliation":[{"name":"Belcolle Hospital, Viterbo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amilcare","family":"Trombetti","sequence":"additional","affiliation":[{"name":"Monaldi Hospital, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biagio","family":"De Pascalis","sequence":"additional","affiliation":[{"name":"Francesco Pispico Hospital, Poggiardo\u2013Lecce, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabatino","family":"Panella","sequence":"additional","affiliation":[{"name":"Villa Maione Clinic, Villaricca\u2013Napoli, 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