{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:06:53Z","timestamp":1777943213207,"version":"3.51.4"},"reference-count":27,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2016,7,9]],"date-time":"2016-07-09T00:00:00Z","timestamp":1468022400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Surg Innov"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:p>Objective. We aim to evaluate the technique of identifying parathyroid glands with carbon nanoparticle suspension (CNPS) in thyroid surgeries from the perspectives of degrees of declining intact parathyroid hormone (iPTH), operation time, and time of postoperative stay. Methods. A total of 156 patients who underwent thyroid surgeries in General Surgical Department of Xiangya Hospital between May 2012 and May 2015 were involved in the study. A total of 78 patients were injected with CNPS during the surgery (CNPS group); the other 78 patients received normal saline (control group). Cases were classified into 3 surgical approaches: conventional partial thyroidectomy, conventional total thyroidectomy, and endoscopic partial thyroidectomy. Degrees of declining iPTH were tested to determine the severity of parathyroid injury. Operation time and postoperative hospital stay time were recorded. A P value of less than .05 was considered statistically significant. Results. For levels of declining iPTH, there was no statistically significant (ss) difference in conventional thyroid surgery. In endoscopic partial thyroidectomy, it was 23.37 \u00b1 16.20 versus 11.94 \u00b1 11.23 pg\/mL ( P = .02, ss). The operation time of conventional total thyroidectomy was 210.10 \u00b1 83.75 versus 164.84 \u00b1 69.22 minutes ( P = .03, ss), while it was 193.04 \u00b1 75.53 versus 127.67 \u00b1 60.06 minutes ( P = .007, ss) in endoscopic thyroidectomy. Conclusions. CNPS is not beneficial for protecting the function of parathyroid gland in thyroid surgery from the perspective of declining iPTH. Applying CNPS in conventional total thyroidectomy and endoscopic partial thyroidectomy will also lead to significantly prolonged operation time.<\/jats:p>","DOI":"10.1177\/1553350615624787","type":"journal-article","created":{"date-parts":[[2016,1,18]],"date-time":"2016-01-18T20:07:45Z","timestamp":1453147665000},"page":"381-389","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Identifying Parathyroid Glands With Carbon Nanoparticle Suspension Does Not Help Protect Parathyroid Function in Thyroid Surgery"],"prefix":"10.1177","volume":"23","author":[{"given":"Xu","family":"Liu","sequence":"first","affiliation":[{"name":"Xiangya Hospital, Central South University, Changsha, Hunan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shi","family":"Chang","sequence":"additional","affiliation":[{"name":"Xiangya Hospital, Central South University, Changsha, Hunan, 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