{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:09:27Z","timestamp":1777943367249,"version":"3.51.4"},"reference-count":42,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T00:00:00Z","timestamp":1676937600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Association supporting the LungenClinic Gro\u00dfhansdorf"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Surg Innov"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The intraoperative evaluation of bronchus perfusion is limited. Hyperspectral Imaging (HSI) is a newly established intraoperative imaging technique that enables a non-invasive, real-time perfusion analysis. Therefore, the purpose of this study was to determine the intraoperative perfusion of bronchus stump and anastomosis during pulmonary resections with HSI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In this prospective, IDEAL Stage 2a study (Clinicaltrials.gov: NCT04784884) HSI measurements were carried out before bronchial dissection and after bronchial stump formation or bronchial anastomosis, respectively. Tissue oxygenation (StO\n                      <jats:sub>2<\/jats:sub>\n                      ; upper tissue perfusion), organ hemoglobin index (OHI), near-infrared index (NIR; deeper tissue perfusion) and tissue water index (TWI) were calculated.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Bronchus stumps showed a reduced NIR (77.82 \u00b1 10.27 vs 68.01 \u00b1 8.95; P = 0,02158) and OHI (48.60 \u00b1 1.39 vs 38.15 \u00b1 9.74; P = &lt;.0001), although the perfusion of the upper tissue layers was equivalent before and after resection (67.42% \u00b1 12.53 vs 65.91% \u00b1 10.40). In the sleeve resection group, we found both a significant decrease in StO 2 and NIR between central bronchus and anastomosis region (StO\n                      <jats:sub>2<\/jats:sub>\n                      : 65.09% \u00b1 12.57 vs 49.45 \u00b1 9.94; P = .044; NIR: 83.73 \u00b1 10.92 vs 58.62 \u00b1 3.01; P = .0063). Additionally, NIR was decreased in the re-anastomosed bronchus compared to central bronchus region (83.73 \u00b1 10.92 vs 55.15 \u00b1 17.56; P = .0029).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Although both bronchus stumps and anastomosis show an intraoperative reduction of tissue perfusion, there is no difference of tissue hemoglobin level in bronchus anastomosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15533506231157165","type":"journal-article","created":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T06:13:04Z","timestamp":1676959984000},"page":"314-323","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Intraoperative Determination of Bronchus Stump and Anastomosis Perfusion with Hyperspectral Imaging"],"prefix":"10.1177","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5595-7414","authenticated-orcid":false,"given":"David B.","family":"Ellebrecht","sequence":"first","affiliation":[{"name":"Department of Surgery, LungClinic Gro\u00dfhansdorf, Gro\u00dfhansdorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Kugler","sequence":"additional","affiliation":[{"name":"Department of Surgery, LungClinic Gro\u00dfhansdorf, Gro\u00dfhansdorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,2,21]]},"reference":[{"key":"bibr1-15533506231157165","doi-asserted-by":"publisher","DOI":"10.1053\/stcs.2001.22493"},{"key":"bibr2-15533506231157165","volume-title":"Bronchopleural Fistula","author":"Salik I","year":"2022"},{"issue":"6","key":"bibr3-15533506231157165","first-page":"330","volume":"7","author":"Sirbu H","year":"2001","journal-title":"Ann Thorac 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