{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:09:40Z","timestamp":1777943380562,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2024,2,22]],"date-time":"2024-02-22T00:00:00Z","timestamp":1708560000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Surg Innov"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Precise preoperative localization of liver tumors facilitates successful surgical procedures, Intraoperative ultrasonography is a sensitive imaging modality. However, the presence of small non-palpable isoechoic intraparenchymal lesions may be challenging intraoperatively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology and Material Description<\/jats:title>\n                    <jats:p>Onyx\u00ae is a non-adhesive liquid agent comprised of ethylene-vinyl alcohol usually used dissolved in dimethyl-sulfoxide and suspended micronized tantalum powder to provide contrast for visualization under fluoroscopy and ultrasonography and a macroscopic black shape. This embolization material has been increasingly used for the embolization of intracranial arteriovenous malformations. We present the novel application of Onyx\u00ae on liver surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Current Status<\/jats:title>\n                    <jats:p>We present the case of a female, 55\u00a0years-old, whose medical history revealed an elective sigmoidectomy (pT3N1a). After 17\u00a0months of follow up, by PET-CT scan, the patient was diagnosed of a small intraparenchymal hypo-attenuated 13\u00a0mm tumor located at segment V consistent with metachronous colorectal liver metastasis. Open metastasectomy was performed, ultrasonography-guided Onyx\u00ae infusion was delivered the day after, intraoperative ultrasonography showed a palpable hyperechoic material with a posterior acoustic shadowing artifact around the lesion. Onyx\u00ae is a promising new tool, without any previous application on liver surgery, feasible with advantages in small not palpable intraparenchymal liver lesions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15533506241236732","type":"journal-article","created":{"date-parts":[[2024,2,22]],"date-time":"2024-02-22T19:34:55Z","timestamp":1708630495000},"page":"220-223","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Onyx\u00ae, A New Tool for Intraoperative Localization of Liver Lesions"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1920-4674","authenticated-orcid":false,"given":"J. J.","family":"Rubio-Garc\u00eda","sequence":"first","affiliation":[{"name":"Servicio de Cirug\u00eda General y Aparato Digestivo, Hospital General Universitario de Alicante, Alicante, Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria y Biom\u00e9dica de Alicante (ISABIAL), Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. J.","family":"Mantilla Pinilla","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Sanitaria y Biom\u00e9dica de Alicante (ISABIAL), Alicante, Spain"},{"name":"Servicio de Radiodiagn\u00f3stico y Radiolog\u00eda Intervencionista, Hospital General Universitario de Alicante, Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Gil S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Sanitaria y Biom\u00e9dica de Alicante (ISABIAL), Alicante, Spain"},{"name":"Servicio de Radiodiagn\u00f3stico y Radiolog\u00eda Intervencionista, Hospital General Universitario de Alicante, Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Villodre Tudela","sequence":"additional","affiliation":[{"name":"Servicio de Cirug\u00eda General y Aparato Digestivo, Hospital General Universitario de Alicante, Alicante, Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria y Biom\u00e9dica de Alicante (ISABIAL), Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Alc\u00e1zar L\u00f3pez","sequence":"additional","affiliation":[{"name":"Servicio de Cirug\u00eda General y Aparato Digestivo, Hospital General Universitario de Alicante, Alicante, Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria y Biom\u00e9dica de Alicante (ISABIAL), Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Melgar Requena","sequence":"additional","affiliation":[{"name":"Servicio de Cirug\u00eda General y Aparato Digestivo, Hospital General Universitario de Alicante, Alicante, Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria y Biom\u00e9dica de Alicante (ISABIAL), Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Rodr\u00edguez Laiz","sequence":"additional","affiliation":[{"name":"Servicio de Cirug\u00eda General y Aparato Digestivo, Hospital General Universitario de Alicante, Alicante, Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria y Biom\u00e9dica de Alicante (ISABIAL), Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Irurzun L\u00f3pez","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Sanitaria y Biom\u00e9dica de Alicante (ISABIAL), Alicante, Spain"},{"name":"Servicio de Radiodiagn\u00f3stico y Radiolog\u00eda Intervencionista, Hospital General Universitario de Alicante, Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. M.","family":"Ramia-\u00c1ngel","sequence":"additional","affiliation":[{"name":"Servicio de Cirug\u00eda General y Aparato Digestivo, Hospital General Universitario de Alicante, Alicante, Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria y Biom\u00e9dica de Alicante (ISABIAL), Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,2,22]]},"reference":[{"key":"bibr1-15533506241236732","doi-asserted-by":"publisher","DOI":"10.14366\/USG.15014"},{"key":"bibr2-15533506241236732","doi-asserted-by":"publisher","DOI":"10.1016\/J.WNEU.2022.11.058"},{"issue":"1","key":"bibr3-15533506241236732","first-page":"46","volume":"5","author":"Aziz H","year":"2022","journal-title":"Cancer Med J"},{"key":"bibr4-15533506241236732","doi-asserted-by":"publisher","DOI":"10.1016\/j.hpb.2020.10.005"},{"key":"bibr5-15533506241236732","doi-asserted-by":"publisher","DOI":"10.1002\/JSO.20039"},{"key":"bibr6-15533506241236732","doi-asserted-by":"publisher","DOI":"10.1002\/BJS5.50140"},{"key":"bibr7-15533506241236732","doi-asserted-by":"publisher","DOI":"10.1016\/j.ciresp.2012.07.010"},{"key":"bibr8-15533506241236732","doi-asserted-by":"publisher","DOI":"10.11622\/SMEDJ.2019137"},{"key":"bibr9-15533506241236732","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2021.04.019"},{"key":"bibr10-15533506241236732","doi-asserted-by":"publisher","DOI":"10.3390\/MPS4030066"},{"key":"bibr11-15533506241236732","doi-asserted-by":"publisher","DOI":"10.1038\/S41467-022-35696-2"},{"key":"bibr12-15533506241236732","doi-asserted-by":"publisher","DOI":"10.24875\/RCHRAD.22000045"}],"container-title":["Surgical Innovation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15533506241236732","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/15533506241236732","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15533506241236732","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T07:24:13Z","timestamp":1777706653000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/15533506241236732"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,22]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["10.1177\/15533506241236732"],"URL":"https:\/\/doi.org\/10.1177\/15533506241236732","relation":{},"ISSN":["1553-3506","1553-3514"],"issn-type":[{"value":"1553-3506","type":"print"},{"value":"1553-3514","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,22]]}}}