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Participants were selected by systematic sampling. In-depth interviews were used to gather data from the participants. Some findings revealed that while ethical principles such as informed consent are highly recommended in clinical trials, participants did not understand and interpret these documents with as much importance as expected. Participants had other priorities and objectives for engaging in the trial; getting rid of the disease onchocerciasis was one of them. Signing the forms was nothing more than a formality for them. 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