{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T22:20:35Z","timestamp":1785450035199,"version":"3.56.0"},"reference-count":17,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,10,26]],"date-time":"2020-10-26T00:00:00Z","timestamp":1603670400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Innovations\ufffd(Phila)"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:p>Tricuspid valve regurgitation (TR) can be associated with poor prognosis. Transcatheter valve technology was adopted to treat the upstream effects of severe TR by placing a transcatheter valve in the inferior vena cava (IVC). In this study, we report off-label transcatheter valve implantation into the stented IVC in patients with severe TR for compassionate use. From September 2018 to February 2020, 6 inoperable patients with severe TR who failed medical treatment underwent percutaneous caval valve implantation (CAVI). Severity of TR was confirmed by intraoperative transesophageal echocardiography. Z-stents (Cook, Inc., Bloomington, IN, USA) were placed in the proximal IVC, and then a transcatheter valve was deployed in the suprahepatic cava without rapid pacing. Six patients, 2 females and 4 males, with a mean \u00b1 SD age of 74.7 \u00b1 8.0 years were included. The procedure was successfully performed in all 6 patients (100%) employing a 29-mm SAPIEN 3 valve (Edwards Lifesciences, Irvine, CA, USA) with supranominal volume. No procedural complication was detected. At 30 days, TR improved from severe to trace in 1 patient, to mild-moderate in 3 patients, and 2 patients remained with severe TR. Among patients with improved TR, left ventricular ejection fraction increased from 47.5% \u00b1 18.5% to 55% \u00b1 20.4% ( P = 0.014). No patient had readmission at 30 days. Four patients needed rehospitalization within 6 months. Percutaneous CAVI is feasible and can be considered as a short-term palliative measure in patients with severe TR. CAVI can improve TR and potentially improve cardiac output in selected patients.<\/jats:p>","DOI":"10.1177\/1556984520957144","type":"journal-article","created":{"date-parts":[[2020,10,27]],"date-time":"2020-10-27T22:47:25Z","timestamp":1603838845000},"page":"577-580","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Percutaneous Inferior Vena Cava Valve Implantation May Improve Tricuspid Valve Regurgitation and Cardiac Output: Lessons Learned"],"prefix":"10.1177","volume":"15","author":[{"given":"Seyed Hossein","family":"Aalaei-Andabili","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Cardiovascular Medicine, University of Maryland, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony A.","family":"Bavry","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Texas Southwestern, Dallas, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Calvin","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Florida, Gainesville, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Arnaoutakis","sequence":"additional","affiliation":[{"name":"Division of Thoracic and Cardiovascular Surgery, Department of Surgery, University of Florida, Gainesville, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. David","family":"Anderson","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Florida, Gainesville, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas M.","family":"Beaver","sequence":"additional","affiliation":[{"name":"Division of Thoracic and Cardiovascular Surgery, Department of Surgery, University of Florida, Gainesville, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,10,26]]},"reference":[{"key":"bibr1-1556984520957144","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2003.09.036"},{"key":"bibr2-1556984520957144","doi-asserted-by":"publisher","DOI":"10.1378\/chest.103.1.226"},{"issue":"4","key":"bibr3-1556984520957144","first-page":"I63","volume":"35","author":"Braunwald NS.","year":"1967","journal-title":"Circulation"},{"key":"bibr4-1556984520957144","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs474"},{"key":"bibr5-1556984520957144","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.09.017"},{"key":"bibr6-1556984520957144","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2007.05.003"},{"key":"bibr7-1556984520957144","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2019.03.004"},{"key":"bibr8-1556984520957144","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp474"},{"key":"bibr9-1556984520957144","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr028"},{"key":"bibr10-1556984520957144","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.01.070"},{"key":"bibr11-1556984520957144","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2017.01.007"},{"key":"bibr12-1556984520957144","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.113.001033"},{"key":"bibr13-1556984520957144","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.117.006061"},{"key":"bibr14-1556984520957144","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.05.101"},{"key":"bibr15-1556984520957144","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.110.944926"},{"key":"bibr16-1556984520957144","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-18-00440"},{"key":"bibr17-1556984520957144","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.07.010"}],"container-title":["Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1556984520957144","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1556984520957144","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1556984520957144","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T11:21:14Z","timestamp":1777461674000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1556984520957144"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,26]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["10.1177\/1556984520957144"],"URL":"https:\/\/doi.org\/10.1177\/1556984520957144","relation":{},"ISSN":["1556-9845","1559-0879"],"issn-type":[{"value":"1556-9845","type":"print"},{"value":"1559-0879","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,26]]}}}