{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T01:34:28Z","timestamp":1792632868607,"version":"4.5.0"},"reference-count":32,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2022,10,30]],"date-time":"2022-10-30T00:00:00Z","timestamp":1667088000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Innovations\ufffd(Phila)"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Venous drainage is often problematic in minimally invasive cardiac surgery (MICS). Here, we describe our experience with a self-expandable stent cannula designed to optimize venous drainage.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      The\n                      <jats:italic>smart canula<\/jats:italic>\n                      <jats:sup>\u00ae<\/jats:sup>\n                      was used in 58 consecutive patients undergoing MICS for mitral valve disease (\n                      <jats:italic>n<\/jats:italic>\n                      = 40), left atrial myxoma (\n                      <jats:italic>n<\/jats:italic>\n                      = 3), left ventricular outflow tract obstruction (\n                      <jats:italic>n<\/jats:italic>\n                      = 1), and aortic valve replacement via a right anterior minithoracotomy (\n                      <jats:italic>n<\/jats:italic>\n                      = 14) procedures. The venous cannula was placed under transesophageal echocardiography guidance to reach the superior vena cava. Vacuum-assisted venous drainage (between \u221220 and \u221235 mm Hg) was used to reach a target flow index of 2.2 L\/min\/m\u00b2 at a core temperature of 34 \u00b0C using a goal-directed perfusion strategy aimed at a minimum DO\n                      <jats:sub>2<\/jats:sub>\n                      of 272 mL\/min\/m\n                      <jats:sup>2<\/jats:sup>\n                      . Cardiopulmonary bypass (CPB) parameters were recorded, and hemolysis-related parameters were analyzed on postoperative days 1 to 7.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Mean body surface area and median body mass index were 1.9 \u00b1 0.2 m\n                      <jats:sup>2<\/jats:sup>\n                      and 25.2 (23.4, 30.2) kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      . Mean CPB and median cross-clamping times were 107.7 \u00b1 24.4 min and 64.5 (53, 75.8) min, and median CPB flow during cardioplegic arrest was 4 (3.6, 4.2) L\/min (median cardiac index 2.1 [2, 2.2] L\/min\/m\u00b2). Venous drainage was considered sufficient by the surgeon in all cases, and insertion and removal were uncomplicated. Mean SvO\n                      <jats:sub>2<\/jats:sub>\n                      during CPB was 80.2% \u00b1 5.5%, and median peak lactate was 10 (8, 14) mg\/dL, indicating sufficient perfusion. Mean venous negative drainage pressure during cross-clamping was 27.2 \u00b1 12.3 mm Hg. Platelets dropped by 73.6 \u00b1 37.5 K\/\u00b5L, lactate dehydrogenase rose by 81.5 (44.3, 140.8) U\/L, and leukocytes rose by 3.4 (2.2, 7.2) K\/\u00b5L on postoperative day 1.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>\n                      The venous\n                      <jats:italic>smart canula<\/jats:italic>\n                      <jats:sup>\u00ae<\/jats:sup>\n                      allows for optimal venous drainage at low negative drainage pressures, facilitating sufficient perfusion in MICS.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15569845221131534","type":"journal-article","created":{"date-parts":[[2022,10,31]],"date-time":"2022-10-31T02:31:10Z","timestamp":1667183470000},"page":"491-498","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Single-Center Experience With a Self-Expandable Venous Cannula During Minimally Invasive Cardiac Surgery"],"prefix":"10.1177","volume":"17","author":[{"given":"Karel M.","family":"Van Praet","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery, German Heart Center Berlin, Germany"},{"name":"DZHK (German Center for Cardiovascular Research), Partner Site Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Kofler","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery, German Heart Center Berlin, Germany"},{"name":"DZHK (German Center for Cardiovascular Research), Partner Site Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Meyer","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery, German Heart Center Berlin, Germany"},{"name":"Berlin Institute of Health, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon H.","family":"S\u00fcndermann","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery, German Heart Center Berlin, Germany"},{"name":"DZHK (German Center for Cardiovascular Research), Partner Site Berlin, Germany"},{"name":"Department of Cardiovascular Surgery, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin, and Berlin Institute of Health, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Hommel","sequence":"additional","affiliation":[{"name":"Institute for Anesthesiology, German Heart Center Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volkmar","family":"Falk","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery, German Heart Center Berlin, Germany"},{"name":"DZHK (German Center for Cardiovascular Research), Partner Site Berlin, Germany"},{"name":"Department of Cardiovascular Surgery, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin, and Berlin Institute of Health, Germany"},{"name":"Translational Cardiovascular Technologies, Institute of Translational Medicine, Department of Health Sciences and Technology, Swiss Federal Institute of Technology (ETH) Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"Kempfert","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery, German Heart Center Berlin, Germany"},{"name":"DZHK (German Center for Cardiovascular Research), Partner Site Berlin, 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