{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T15:53:14Z","timestamp":1777737194497,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Innovations\ufffd(Phila)"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>This study aimed to compare the outcomes of minimally invasive aortic valve replacement (MICS-AVR) versus transfemoral transcatheter aortic valve replacement (TF-TAVR) in Asian patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We conducted a retrospective, observational, single-center study in Japan, including cases of MICS-AVR ( n = 202) and TF-TAVR ( n = 248) between 2014 and 2021. In a total of 450 cases, propensity score matching was performed at a ratio of 1:1, resulting in 96 pairs. Furthermore, we performed competing-risk regression and mediation analyses to determine the treatment effect on outcomes of interests, considering death as a competing risk, and to evaluate the mediation effect of paravalvular leak (PVL) severity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>There were similar incidences of all-cause death, cardiac death, stroke and cerebral hemorrhage, and aortic valve reintervention between the 2 groups. However, the TF-TAVR cohort had a longer hospital length of stay and higher rates of significant PVL compared with the MICS-AVR cohort. Multivariable-adjusted Cox regression analyses revealed that heart failure hospitalization (hazard ratio [HR] = 0.129, 95% confidence interval [CI]: 0.038 to 0.445, p = 0.001) and permanent pacemaker implantation (HR = 0.050, 95% CI: 0.006 to 0.409, p = 0.005) favored MICS-AVR. Competing-risk regression analyses confirmed similar findings. All outcomes were unrelated to PVL severity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>To our knowledge, this is the first comparative study of clinical outcomes in Asian patients undergoing MICS-AVR versus TF-TAVR, revealing that MICS-AVR could be a feasible and efficient alternative to TF-TAVR. Future larger-scale randomized controlled trials are needed to validate the present results.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15569845231205587","type":"journal-article","created":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T07:18:58Z","timestamp":1699341538000},"page":"547-556","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Minimally Invasive Surgical Versus Transcatheter Aortic Valve Replacement: A Retrospective Observational Single-Center Study in Japan"],"prefix":"10.1177","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4742-7653","authenticated-orcid":false,"given":"Hiroyuki","family":"Yamamoto","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine, Narita-Tomisato Tokushukai Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taisuke","family":"Nakayama","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Chiba-Nishi General Hospital, Matsudo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Ishii","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Tokyo Shinagawa Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshitsugu","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Chiba-Nishi General Hospital, Matsudo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,11,7]]},"reference":[{"key":"bibr1-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-010-0268-x"},{"key":"bibr2-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1814052"},{"key":"bibr3-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1816885"},{"key":"bibr4-15569845231205587","doi-asserted-by":"publisher","DOI":"10.21037\/jtd-20-1968"},{"key":"bibr5-15569845231205587","doi-asserted-by":"publisher","DOI":"10.21037\/jtd-20-2233"},{"key":"bibr6-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1136\/openhrt-2020-001535"},{"key":"bibr7-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1007\/s11748-019-01234-z"},{"key":"bibr8-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1053\/j.semtcvs.2011.04.005"},{"key":"bibr9-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs255"},{"key":"bibr10-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1999.10474144"},{"key":"bibr11-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1177\/1536867X1001000104"},{"key":"bibr12-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1037\/0022-3514.51.6.1173"},{"key":"bibr13-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2016.12.028"},{"key":"bibr14-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2018.01.273"},{"key":"bibr15-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.24970"},{"key":"bibr16-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1007\/s12928-018-0546-5"},{"key":"bibr17-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz275"},{"key":"bibr18-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2020.09.063"},{"key":"bibr19-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw225"},{"key":"bibr20-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.01.047"},{"key":"bibr21-15569845231205587","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11206117"},{"key":"bibr22-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpcardiol.2021.100957"},{"key":"bibr23-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2015.01.008"},{"key":"bibr24-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.08.035"},{"key":"bibr25-15569845231205587","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivx355"}],"container-title":["Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15569845231205587","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/15569845231205587","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15569845231205587","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T11:18:57Z","timestamp":1777461537000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/15569845231205587"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["10.1177\/15569845231205587"],"URL":"https:\/\/doi.org\/10.1177\/15569845231205587","relation":{},"ISSN":["1556-9845","1559-0879"],"issn-type":[{"value":"1556-9845","type":"print"},{"value":"1559-0879","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11]]}}}