{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T15:54:06Z","timestamp":1777737246718,"version":"3.51.4"},"reference-count":34,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100006953","name":"new england medical center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006953","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Innovations&amp;#65533;(Phila)"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The optimal approach and choice of initial aortic valve replacement (AVR) is evolving in the growing era of transcatheter AVR. Further survival and hemodynamic data are needed to compare the emerging role of rapid deployment (rdAVR) versus stented (sAVR) valve options for AVR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The Northern New England Cardiovascular Database was queried for patients undergoing either isolated AVR or AVR + coronary artery bypass grafting (CABG) with rdAVR or sAVR aortic valves between 2015 and 2021. Exclusion criteria included endocarditis, mechanical valves, dissection, emergency case status, and prior sternotomy. This resulted in a cohort including 1,616 sAVR and 538 rdAVR cases. After propensity weighting, procedural characteristics, hemodynamic variables, and survival outcomes were examined.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The breakdown of the overall cohort (2,154) included 1,164 isolated AVR (222 rdAVR, 942 sAVR) and 990 AVR + CABG (316 rdAVR, 674 sAVR). After inverse propensity weighting, cohorts were well matched, notable only for more patients &lt;50 years in the sAVR group (4.0% vs 1.9%, standardized mean difference [SMD] = \u22120.12). Cross-clamp (89 vs 64 min, SMD = \u22120.71) and cardiopulmonary bypass (121 vs 91 min, SMD = \u22120.68) times were considerably longer for sAVR versus rdAVR. Immediate postreplacement aortic gradient decreased with larger valve size but did not differ significantly between comparable sAVR and rdAVR valve sizes or overall (6.5 vs 6.7 mm Hg, SMD = 0.09). Implanted rdAVR tended to be larger with 51% either size L or XL versus 37.4% of sAVR \u226525 mm. Despite a temporal decrease in pacemaker rate within the rdAVR cohort, the overall pacemaker frequency was less in sAVR versus rdAVR (4.4% vs 7.4%, SMD = 0.12), and significantly higher rates were seen in size L (10.3% vs 3.7%,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.002) and XL (15% vs 5.6%,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.004) rdAVR versus sAVR. No significant difference in major adverse cardiac events (4.6% vs 4.6%, SMD = 0.01), 30-day survival (1.5% vs 2.6%, SMD = 0.08), or long-term survival out to 4 years were seen between sAVR and rdAVR.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Rapid deployment valves offer a safe alternative to sAVR with significantly decreased cross-clamp and cardiopulmonary bypass times. Despite larger implantation sizes, we did not appreciate a comparative difference in immediate postoperative gradients, and although pacemaker rates are improving, they remain higher in rdAVR compared with sAVR. Longer-term hemodynamic and survival follow-up are needed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15569845231223504","type":"journal-article","created":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T03:53:01Z","timestamp":1707191581000},"page":"54-63","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["The Northern New England Rapid Deployment Valve Experience: Survival and Procedural Outcomes From 2015 to 2021"],"prefix":"10.1177","volume":"19","author":[{"given":"John M.","family":"Fallon","sequence":"first","affiliation":[{"name":"Department of Cardiac Surgery, Maine Medical Center, Portland, ME, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David J.","family":"Malenka","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cathy S.","family":"Ross","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niveditta","family":"Ramkumar","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shravanthi M.","family":"Seshasayee","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin M.","family":"Westbrook","sequence":"additional","affiliation":[{"name":"Catholic Medical Center, Manchester, NH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fuyuki","family":"Hirashima","sequence":"additional","affiliation":[{"name":"University of Vermont Medical Center, Burlington, VT, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reed D.","family":"Quinn","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Maine Medical Center, Portland, ME, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,2,6]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2010.10.007"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2014.09.022"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivu102"},{"key":"e_1_3_2_5_2","first-page":"732","article-title":"Aortic cross-clamp time, new prostheses, and outcome in aortic valve replacement","volume":"21","author":"Ranucci M","year":"2012","unstructured":"Ranucci M, Frigiola A, Menicanti L, et al. 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