{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T17:01:57Z","timestamp":1793293317664,"version":"4.5.0"},"reference-count":24,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Innovations\ufffd(Phila)"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Venovenous (VV) extracorporeal membrane oxygenation (ECMO) cannulation may pose venous access challenges. Subclavian vein (SCV) cannulation is an alternative site. This study hypothesizes that SCV access is a safe alternative in VV ECMO.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This is a single-center, retrospective study of peripheral VV ECMO that was stratified by SCV cannulation. Each site was considered as a separate cannulation event. Descriptive statistics, groupwise comparisons, and mixed-effects logistic regression were used. Primary endpoints included cannulation-specific complications and ECMO-related adverse events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      From 2020 to 2023, 157 patients were supported with VV ECMO. The cohort was 57% male patients with a median age of 44 (34 to 56) years and a median body mass index of 34 (28 to 44) kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      . Thirty-five percent of patients (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 55) had an SCV cannula during their ECMO course. Both groups had similar pre-ECMO variables, except for higher rates of COVID-19 (69% [\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 38] vs 49% [\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 49],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.016) in the SCV cohort. There was no unadjusted survival difference (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.8). There were 392 unique cannulation events. SCV cannulations were more commonly employed for additional cannulas and transitioning to single-site dual-lumen cannulation (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). There was an increased cannulation-associated pneumothorax rate in the SCV arm (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001) when compared with all non-SCV sites. Mixed-effects logistic regression showed no site-related differences in adverse events or complication rates.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Between the SCV and non-SCV groups, there was no difference in site-related adverse events or complications. This study supports the use of SCV cannulation as a viable alternative in patients supported with VV ECMO.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15569845251375502","type":"journal-article","created":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T08:36:10Z","timestamp":1759480570000},"page":"484-493","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Outcomes of Subclavian Vein Cannulation in Venovenous Extracorporeal Membrane Oxygenation: A Single-Center Retrospective Study"],"prefix":"10.1177","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8859-6491","authenticated-orcid":false,"given":"Sagar B.","family":"Dave","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA, USA"},{"name":"Department of Anesthesiology, Division of Critical Care, Emory University School of Medicine, Atlanta, GA, USA"},{"name":"Emory Critical Care Center, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose B.","family":"Trinidad","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Zalesky","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA, USA"},{"name":"Department of Anesthesiology, Division of Critical Care, Emory University School of Medicine, Atlanta, GA, USA"},{"name":"Emory Critical Care Center, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Creel-Bulos","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA, USA"},{"name":"Department of Anesthesiology, Division of Critical Care, Emory University School of Medicine, Atlanta, GA, USA"},{"name":"Emory Critical Care Center, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Leiendecker","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Division of Critical Care, Emory University School of Medicine, Atlanta, GA, USA"},{"name":"Emory Critical Care Center, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepa M.","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA, USA"},{"name":"Department of Anesthesiology, Division of Critical Care, Emory University School of Medicine, Atlanta, GA, USA"},{"name":"Emory Critical Care Center, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Casey Frost","family":"Miller","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Morris","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josh","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mani","family":"Daneshmand","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6687-3953","authenticated-orcid":false,"given":"Craig S.","family":"Jabaley","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Division of Critical Care, Emory University School of Medicine, Atlanta, GA, USA"},{"name":"Emory Critical Care Center, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Javidfar","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, GA, 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