{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:27:21Z","timestamp":1791271641282,"version":"4.1.0"},"reference-count":27,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Photobiomodulation, Photomedicine, and Laser Surgery"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Phototherapy is a well-established treatment for various chronic inflammatory dermatoses, yet data on its safety and efficacy in geriatric populations remain limited. Older adults face unique clinical challenges due to age-related physiological changes, comorbidities, and polypharmacy, which may impact treatment responses and tolerance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>This study aimed to evaluate the safety, efficacy, and clinical outcomes of phototherapy in elderly patients treated over a 10-year period at a tertiary dermatology center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A retrospective analysis was conducted on patients aged \u226565 years who received \u22658 sessions of phototherapy between 2013 and 2023. Narrowband UVB (NB-UVB), systemic psoralen plus ultraviolet A (PUVA), and localized PUVA therapies were administered using standardized protocols. Diagnosis-specific clinical criteria were used to assess treatment response. Data on adverse events, recurrence, and the need for additional sessions were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The study included 149 patients (mean age 70.2 \u00b1 5.0 years; 44.3% female, 55.7% male) with 19 distinct dermatologic diagnoses. The most common indications were psoriasis (24.8%), generalized pruritus (18.1%), mycosis fungoides (11.4%), and lichen planus (6.7%). NB-UVB was used in 85.2% patients, while 10.1% received local PUVA and 4.7% underwent systemic PUVA. Overall, 83.2% of patients demonstrated clinical improvement. The highest treatment durations and cumulative doses were observed in mycosis fungoides (mean 9.3 months, 88.7 J\/cm\n                      <jats:sup>2<\/jats:sup>\n                      ) and lichen planus (9.5 months, 59.6 J\/cm\n                      <jats:sup>2<\/jats:sup>\n                      ). Adverse events occurred in 12.8%, predominantly mild erythema and pruritus. Recurrence was noted at 18.1%, and 16.1% required additional sessions. Despite 40.9% of patients using photosensitizing medications, no severe phototoxic reactions were observed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Phototherapy is a safe, effective, and well-tolerated treatment option for elderly patients with a variety of dermatologic conditions. The high clinical response rates, even in complex and refractory cases, support its continued use in this population. With its favorable safety profile and non-systemic nature, phototherapy remains a particularly suitable modality in the context of multimorbidity and polypharmacy. Further large-scale, multicenter prospective studies are warranted to establish standardized protocols tailored for geriatric populations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15578550251364196","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T16:43:22Z","timestamp":1768841002000},"page":"592-599","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Phototherapy in Geriatric Patients: Ten Years of Clinical Experience in a Tertiary Dermatology Clinic"],"prefix":"10.1177","volume":"43","author":[{"given":"G\u00f6k\u00e7e I\u015f\u0131l","family":"Kurmu\u015f","sequence":"first","affiliation":[{"name":"Department of Dermatology &amp; Venereology, Ankara Etlik City Hospital, Ankara, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilek","family":"Mente\u015fo\u011flu","sequence":"additional","affiliation":[{"name":"Department of Dermatology &amp; Venereology, Ankara Etlik City Hospital, Ankara, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selda Pelin","family":"Kartal","sequence":"additional","affiliation":[{"name":"Department of Dermatology &amp; Venereology, Ankara Etlik City Hospital, Ankara, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,1,19]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2005.02607.x"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.4235\/agmr.20.0048"},{"key":"e_1_3_2_4_2","doi-asserted-by":"crossref","unstructured":"Widodo AA Jacoeb TNA Novianto E et al. Differences of minimum erythema dose (MED) in Fitzpatrick IV skin type adults and elderly with an exposure of narrowband ultraviolet B (NB-UVB). In: Proceedings of the 23rd Regional Conference of Dermatology. SCITEPRESS-Science and Technology Publications; 2018; pp. 73\u201377.","DOI":"10.5220\/0008151100730077"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.03.017"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.abd.2021.03.001"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.12788\/cutis.0307"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S215308"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/ced.12626"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20185468"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.4103\/ijd.ijd_184_23"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.12788\/cutis.0617"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2021.08.014"},{"key":"e_1_3_2_14_2","volume-title":"Phototherapy Treatment Guide","author":"Kundakc\u0131 N","year":"2018","unstructured":"Kundakc\u0131 N, , \u00d6zt\u00fcrk G., editors. Phototherapy Treatment Guide. Turkish Society of Dermatology Publications, Galenos Publishing House: Istanbul; 2018. Publication No: 5. ISBN: 978-975-96175-4-7."},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.05.014"},{"key":"e_1_3_2_16_2","first-page":"175","article-title":"Psoriasis in the elderly","volume":"23","author":"Ruiz-Villaverde R","year":"2015","unstructured":"Ruiz-Villaverde R, , Garrido-Colmenero C, , Martinez-Peinado CM, et al. Psoriasis in the elderly. Do we Know How to Manage It? Hong Kong J Dermatol Venereol, 2015; 23:175\u2013182.","journal-title":"Do we Know How to Manage It? Hong Kong J Dermatol Venereol"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1080\/14656566.2018.1444752"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2005.00032.x"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2007.03048.x"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASW.0000803256.62585.d5"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2003.80"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2009.03500.x"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-0283"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12873"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-015-0160-6"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12723"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0781.2003.00051.x"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2008.02970.x"}],"container-title":["Photobiomodulation, Photomedicine, and Laser Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15578550251364196","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/15578550251364196","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15578550251364196","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T07:27:00Z","timestamp":1777706820000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1177\/15578550251364196"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":27,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1177\/15578550251364196"],"URL":"https:\/\/doi.org\/10.1177\/15578550251364196","relation":{},"ISSN":["2578-5478","2578-5478"],"issn-type":[{"value":"2578-5478","type":"print"},{"value":"2578-5478","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12]]}}}