{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:11:24Z","timestamp":1777943484056,"version":"3.51.4"},"reference-count":29,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lymphatic Research and Biology"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To determine whether a 4-day, twice-daily complete decongestive therapy (CDT) intervention effectively reduces limb volume in pediatric patients with primary and secondary lymphedema.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A retrospective cohort study was conducted using rehabilitation records of children aged 5\u201317 years from Camp Watchme, a North American summer camp providing lymphedema interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Over 4 years, 38 unique campers contributed 66 records for analysis. The majority were female (68.42%), with a mean age of 9.30 \u00b1 2.66 years. Lower extremity limb volume demonstrated statistically significant reductions across all 4 years (2021,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.011; 2022,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.030; 2023,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001; 2024,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001). Cumulative analysis of upper extremities (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 16) also showed significant volume reduction (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.042,\n                      <jats:italic toggle=\"yes\">r<\/jats:italic>\n                      = 0.50). Daily measurement tracking (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 43) indicated consistent percent volume decreases, with confidence intervals supporting a meaningful change for lower extremity limb volume differences across 4 years.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>An intensive, short-duration CDT intervention significantly reduces limb volume in pediatric patients with lymphedema. Future research should explore long-term effects, optimize CDT protocols, and assess broader functional and psychosocial outcomes to enhance pediatric lymphedema management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15578585251367334","type":"journal-article","created":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T21:03:03Z","timestamp":1759870983000},"page":"283-290","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Effectiveness of Twice-Daily Complete Decongestive Therapy in Reducing Limb Volume in Children with Lymphedema: A Retrospective Study"],"prefix":"10.1177","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5113-3397","authenticated-orcid":false,"given":"David","family":"Doubblestein","sequence":"first","affiliation":[{"name":"A.T. Still University, Department of Physical Therapy, Mesa, Arizona 85206, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deanne","family":"Fay","sequence":"additional","affiliation":[{"name":"A.T. Still University, Department of Physical Therapy, Mesa, Arizona 85206, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Brunskill","sequence":"additional","affiliation":[{"name":"Brylan\u2019s Feat Foundation, Scottsdale, Arizona 85251, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Betty","family":"Westbrook","sequence":"additional","affiliation":[{"name":"Brylan\u2019s Feat Foundation, Scottsdale, Arizona 85251, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brittany","family":"Williams","sequence":"additional","affiliation":[{"name":"Brylan\u2019s Feat Foundation, Scottsdale, Arizona 85251, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,10,8]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"crossref","unstructured":"Greene AK. 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