{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T21:20:01Z","timestamp":1789507201398,"version":"build-2803163510"},"reference-count":54,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Mens Health"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:p>No prior study has evaluated the impacts of Ramadan intermittent fasting (RIF) on oxidant\/antioxidant stress (OS\/AOS) biomarkers in patients with chronic obstructive pulmonary disease (COPD). The aim of this study was to assess the impacts of RIF on some OS\/AOS biomarkers measured in male patients with stable COPD. Fifteen COPD patients (mean age: 71 \u00b1 6 years) fasting Ramadan in 2017 volunteered to take part in the study. Three sessions (before Ramadan [BR], end Ramadan [ER], after Ramadan [AR]) were selected. Blood samples of OS (homocysteine [\u03bcmol\/L], thiobarbituric acid reactive substances [TBARS, \u03bcmol\/L]) and AOS (catalase [U\/ml], ceruloplasmin [g\/L], superoxide dismutase [SOD, ng\/ml], zinc [\u00b5mol\/L], albumin [g\/L]) biomarkers were consistently taken 4.5 to 2.5 hr before the iftar. Findings were analyzed by applying Friedman or Kruskal\u2013Wallis ANOVA. Comparisons of the number of patients with high OS [high homocysteine and\/or TBARS] and low AOS (low catalase and\/or ceruloplasmin and\/or SOD and\/or zinc and\/or albumin) blood values between the three sessions were performed using the Cochran test. The median \u00b1 interquartile of homocysteine (BR: 21.48 [18.98\u201324.49], ER: 23.15 [21.77\u201326.45], AR: 24.87 [21.91\u201337.12]), ceruloplasmin (BR: 0.27 [0.24\u20130.30], ER: 0.28 [0.26\u20130.33], AR: 0.28 [0.25\u20130.32]), SOD (BR: 288.00 [112.00\u2013400.00], ER: 182.00 [152.00\u2013386.00], AR: 234.00 [190.00\u2013420.00]) and the mean \u00b1 SD of TBARS (BR: 5.66 \u00b1 1.26, ER: 4.59 \u00b1 0.78, AR: 5.29 \u00b1 1.69), catalase (BR: 120.97 \u00b1 54.62, ER: 106.73 \u00b1 50.92, AR: 137.39 \u00b1 40.88), zinc (BR: 11.85 \u00b1 2.01, ER: 12.47 \u00b1 2.34, AR: 12.21 \u00b1 2.58) and albumin (BR: 39.78 \u00b1 3.19, ER: 40.74 \u00b1 2.26, AR: 40.56 \u00b1 2.38) were not significantly affected by RIF. The number of patients with high OS (BR [ n = 13], ER [ n = 15], AR [ n = 14]) or low AOS (BR [ n = 12], ER [ n = 13], AR [ n = 13]) statuses were not significantly influenced by RIF. In conclusion, RIF did not induce any significant statistical or clinical changes in OS\/AOS biomarkers or statuses in COPD patients.<\/jats:p>","DOI":"10.1177\/1557988319848281","type":"journal-article","created":{"date-parts":[[2019,5,3]],"date-time":"2019-05-03T04:06:41Z","timestamp":1556856401000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["The Impacts of Ramadan Intermittent Fasting on Oxidant\/Antioxidant Stress Biomarkers of Stable Chronic Obstructive Pulmonary Disease Male Patients"],"prefix":"10.1177","volume":"13","author":[{"given":"Sawssan","family":"Mrad","sequence":"first","affiliation":[{"name":"Laboratory of Biochemistry, Farhat Hached Hospital, Sousse, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadhemi","family":"Rejeb","sequence":"additional","affiliation":[{"name":"Pulmonary Department, Farhat Hached Hospital, Sousse, 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