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Carob, a pod-bearing tree native to the Mediterranean, exhibits promising therapeutic potential for various aspects of male reproductive health. Carob consumption may positively affect sperm count, motility, and morphology in infertile men. The proposed mechanisms involve antioxidant activity, improved blood flow, and enhanced energy production within sperm. Carob\u2019s richness in antioxidants like polyphenols and flavonoids might counteract oxidative stress, a major contributor to sperm dysfunction. Carob may influence male sex hormones by potentially stimulating testosterone production and inhibiting estrogen conversion. While carob demonstrates promise as a natural supplement for male fertility, more robust research is necessary to solidify its therapeutic role. This exploration could pave the way for the development of novel dietary or nutraceutical interventions to address male infertility. While preliminary research suggests positive effects on sperm health and potential hormonal influence, robust clinical trials are needed to solidify carob\u2019s therapeutic efficacy. This exploration paves the way for future research on carob as a natural supplement and potentially opens doors for novel dietary or nutraceutical interventions to address male infertility.<\/jats:p>","DOI":"10.1177\/15579883241290835","type":"journal-article","created":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T02:38:22Z","timestamp":1729564702000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Ceratonia Siliqua L: A Natural Compound with Big Impact on Male Reproductive System"],"prefix":"10.1177","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1189-9037","authenticated-orcid":false,"given":"Amir Masoud","family":"Firouzabadi","sequence":"first","affiliation":[{"name":"MSc of Medical Physiology Graduated from Shahid Sadoughi University of Medical Sciences, Yazd, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,10,21]]},"reference":[{"key":"bibr1-15579883241290835","doi-asserted-by":"publisher","DOI":"10.1016\/j.hermed.2022.100596"},{"key":"bibr2-15579883241290835","doi-asserted-by":"publisher","DOI":"10.1111\/jpn.12651"},{"key":"bibr3-15579883241290835","doi-asserted-by":"publisher","DOI":"10.25258\/ijcprr.v8i02.9199"},{"key":"bibr4-15579883241290835","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)32667-2"},{"key":"bibr5-15579883241290835","unstructured":"Aghajani M. 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