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Latino men who have sex with men (LMSM) and Latino seasonal farmworkers (LSW) are two groups at the highest risk of HCV. In response, we developed and validated \u201cHEPCA-Lat: Prueba de Conocimientos sobre Hepatitis C para Adultos Latinos,\u201d a bilingual English\/Spanish HCV knowledge scale. First, we identified 14 unique HCV scales. Then, experts and community health workers identified 43 items to include in HEPCA-Lat. From 2018 to 2020, we recruited participants from community health organizations in South Florida to complete a cross-sectional questionnaire. We conducted Item-Total Correlation, Principal Component, and reliability (random splits, Cronbach\u2019s alpha, mean inter-item correlation) analyses to develop and validate the final HEPCA-Lat. We used regression analyses to examine associations with HCV knowledge. Of 208 participants, 89 were LMSM and 127 were LSW. Of 43 unweighted items identified for initial inclusion, a correlation threshold of &gt;0.5 was used, and 20 items were retained. Items loaded onto 2 components: \u201cHCV prevention\u201d and \u201cLiving with HCV\u201d (55.4% of variance). HCV knowledge was low: LMSM correctly answered 44.6% and LSW 14.5% of items. Future research could focus on (a) applying the HEPCA-Lat scale in pre- and post-intervention assessments to evaluate changes in HCV knowledge and (b) refining the HEPCA-Lat scale to a concise version for broader use among the general Latino population.<\/jats:p>","DOI":"10.1177\/15579883261449061","type":"journal-article","created":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T04:59:40Z","timestamp":1786424380000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Development and Validation of HEPCA-Lat: A Bilingual Hepatitis C Virus Knowledge Scale for Latino Men"],"prefix":"10.1177","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3500-8507","authenticated-orcid":false,"given":"Cho-Hee","family":"Shrader","sequence":"first","affiliation":[{"name":"Division of Nursing Science, School of Nursing, Rutgers University, Newark, NJ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Arroyo-Flores","sequence":"additional","affiliation":[{"name":"Fors Marsh, Arlington, VA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edda","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences, University of Miami, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lacey","family":"Despres","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences, University of Miami, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Castaneda","sequence":"additional","affiliation":[{"name":"University of California Los Angeles, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6316-2822","authenticated-orcid":false,"given":"Isaac","family":"Nkrumah","sequence":"additional","affiliation":[{"name":"Division of Nursing Science, School of Nursing, Rutgers University, Newark, NJ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariano","family":"Kanamori","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences, University of Miami, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,8,10]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/wics.101"},{"key":"e_1_3_3_3_1","doi-asserted-by":"crossref","unstructured":"Allison W. 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