{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T03:28:55Z","timestamp":1785209335486,"version":"3.55.0"},"reference-count":43,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2024,7,12]],"date-time":"2024-07-12T00:00:00Z","timestamp":1720742400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,7,12]],"date-time":"2024-07-12T00:00:00Z","timestamp":1720742400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Breast Disease"],"published-print":{"date-parts":[[2024,7,12]]},"abstract":"<jats:p>\n                    Paget disease (PD) of the breast is a rare malignancy of the nipple\u2013areola region that is almost always associated with an underlying\n                    <jats:italic toggle=\"yes\">in situ<\/jats:italic>\n                    or invasive carcinoma. It can affect both women and men. It is more commonly seen in postmenopausal women. Clinical features may be the only sign of cancer during the initial presentation, making a diagnosis challenging. Early changes in PD include itching, scaling, and erythema of the nipple that can mimic other benign conditions, such as eczema. Histologically, it is characterized by an intraepidermal proliferation of malignant glandular epithelial cells in the nipple\u2013areolar region. Imaging plays an important role in evaluating the extent of involvement and in deciding patient management. This article will provide an overview of the clinical features, histopathology, associated imaging findings, and management of PD.\n                  <\/jats:p>","DOI":"10.1177\/15581551241289263","type":"journal-article","created":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T22:57:19Z","timestamp":1767653839000},"page":"293-301","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Paget disease of the breast: An often-overlooked malignancy"],"prefix":"10.1177","volume":"43","author":[{"given":"Cherie M","family":"Kuzmiak","sequence":"first","affiliation":[{"name":"UNC School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7134-6138","authenticated-orcid":false,"given":"Romuald","family":"Ferre","sequence":"additional","affiliation":[{"name":"Radiology Department, TDH, Timmins, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,11,11]]},"reference":[{"key":"e_1_3_3_2_2","first-page":"184","volume-title":"WHO Classification of Tumours: Breast Tumours","author":"Albarracin CT","year":"2019","unstructured":"Albarracin CT, Baldewijns M, Lester SC. Epithelial tumours of the breast: Paget disease. In: WHO Classification of Tumours: Breast Tumours. 5th ed. Lyon, France: International Agency for Research on Cancer, 2019, pp. 184\u2013185.","edition":"5"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.3233\/BD-200439"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.21037\/tcr-20-3492"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2006.06.010"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-013-2661-4"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2008.508"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2019.03.025"},{"key":"e_1_3_3_9_2","volume-title":"StatPearls","author":"Yasir M","year":"2023","unstructured":"Yasir M, Khan M, Lotfollahzadeh S. Mammary Paget disease. In: StatPearls. 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