{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T01:16:25Z","timestamp":1779930985329,"version":"3.53.1"},"reference-count":26,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2018,7,17]],"date-time":"2018-07-17T00:00:00Z","timestamp":1531785600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Hand (New York, N,Y.)"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:p>Background: The objective of the study is to examine the short-term and long-term efficacy of surgical treatment of carpal tunnel syndrome (CTS) compared with conservative treatment (ie, splint, steroid injection, or physical therapy). Methods: Two reviewers searched the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, and PEDro up to September 2017. Quality appraisal and data extraction were performed in duplicate. Patient self-reported functional and symptom changes, as well as improvement of electrophysiological studies, were assessed as outcomes. Meta-analyses were performed in RevMan. Results: From 1438 studies identified after searching, 10 remained for analysis after exclusion criteria were applied. Moderate-quality evidence indicated that surgical interventions were superior to splint or steroid injection at 6 months with a weighted mean difference of 0.25 (95% confidence interval [CI], 0.07-0.44) for functional status and 0.64 (95% CI, 0.07-1.21) for symptom severity. The surgical group had better nerve conduction outcomes at 6 months (0.57 [95% CI, 0.05-0.50] ms). No significant differences were observed at 3 or 12 months. Conclusions: Both surgical and conservative interventions provide treatment benefits in CTS. Further studies on long-term outcome are needed.<\/jats:p>","DOI":"10.1177\/1558944718787892","type":"journal-article","created":{"date-parts":[[2018,7,17]],"date-time":"2018-07-17T09:54:39Z","timestamp":1531821279000},"page":"13-22","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":66,"title":["Comparison of the Short-Term and Long-Term Effects of Surgery and Nonsurgical Intervention in Treating Carpal Tunnel Syndrome: A Systematic Review and Meta-Analysis"],"prefix":"10.1177","volume":"15","author":[{"given":"Qiyun","family":"Shi","sequence":"first","affiliation":[{"name":"Western University, London, ON, Canada"},{"name":"St. Joseph\u2019s Health Centre, London, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5098-4840","authenticated-orcid":false,"given":"Pavlos","family":"Bobos","sequence":"additional","affiliation":[{"name":"Western University, London, ON, Canada"},{"name":"St. Joseph\u2019s Health Centre, London, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0946-2493","authenticated-orcid":false,"given":"Emily A.","family":"Lalone","sequence":"additional","affiliation":[{"name":"Western University, London, ON, Canada"},{"name":"St. Joseph\u2019s Health Centre, London, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Warren","sequence":"additional","affiliation":[{"name":"University of Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joy C.","family":"MacDermid","sequence":"additional","affiliation":[{"name":"Western University, London, ON, Canada"},{"name":"St. Joseph\u2019s Health Centre, London, ON, Canada"},{"name":"McMaster University, Hamilton, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,7,17]]},"reference":[{"key":"bibr1-1558944718787892","unstructured":"American Academy of Orthopaedic Surgeons. Appropriate Use Criteria for the Management of Carpal Tunnel Syndrome. http:\/\/www.orthoguidelines.org\/go\/auc\/auc.cfm?auc_id=224989. Published December 9, 2016. Accessed July 2, 2018."},{"key":"bibr2-1558944718787892","unstructured":"American Academy of Orthopaedic Surgeons. Management of Carpal Tunnel Syndrome Evidence-Based Clinical Practice Guideline. www.aaos.org\/ctsguideline. Published February 29, 2016. Accessed July 2, 2018."},{"key":"bibr3-1558944718787892","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6963-4-38"},{"issue":"1","key":"bibr4-1558944718787892","first-page":"192","volume":"27","author":"Awan AS","year":"2015","journal-title":"J Ayub Med Coll Abbottabad"},{"key":"bibr5-1558944718787892","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199804000-00005"},{"key":"bibr6-1558944718787892","doi-asserted-by":"publisher","DOI":"10.1016\/S0266-7681(99)90009-8"},{"key":"bibr7-1558944718787892","doi-asserted-by":"publisher","DOI":"10.1097\/WNP.0000000000000243."},{"key":"bibr8-1558944718787892","unstructured":"Copenhagen: The Nordic Cochrane Centre TCC. Review Manager (RevMan) [Computer program]. Version 5.3. 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