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Methods: A Monte Carlo simulation model was used to estimate the lifetime direct and indirect costs associated with nonoperative and operative treatment of CTS, and its utility to patients. Results: Operative treatment of CTS had a lower total cost and a higher utility when compared with nonoperative treatment. Conclusions: CTS surgery is clearly a cost-effective treatment strategy that should be included in the societal perspective regarding evolving costs and savings associated with health care.<\/jats:p>","DOI":"10.1177\/1558944718810855","type":"journal-article","created":{"date-parts":[[2018,11,12]],"date-time":"2018-11-12T06:57:16Z","timestamp":1542005836000},"page":"NP1-NP5","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":32,"title":["The Direct and Indirect Costs to Society of Carpal Tunnel Release"],"prefix":"10.1177","volume":"15","author":[{"given":"Alexandra S.","family":"Gabrielli","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex C.","family":"Lesiak","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Fowler","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,11,12]]},"reference":[{"key":"bibr1-1558944718810855","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2011.203"},{"key":"bibr2-1558944718810855","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.2.153"},{"key":"bibr3-1558944718810855","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.3351"},{"key":"bibr4-1558944718810855","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhsa.2012.04.035"},{"key":"bibr5-1558944718810855","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.20430"},{"key":"bibr6-1558944718810855","unstructured":"US Bureau of Labor Statistics. Nonfatal occupational injuries and illnesses requiring days away from work, 2015. Washington, DC: US Department of Labor; 2015. https:\/\/www.bls.gov\/news.release\/pdf\/osh2.pdf. 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