{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T19:04:44Z","timestamp":1777662284071,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T00:00:00Z","timestamp":1686182400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Hand (New York, N,Y.)"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:p>The ongoing outbreak of the monkeypox virus (now referred to as \u201cmpox\u201d) was deemed a public health emergency by the World Health Organization in 2022. The United States now reports the highest number of mpox cases, with 29\u2009980 cases and 21 deaths as of January 11, 2023. The most common presenting symptom is a pruritic, vesicular rash that commonly involves the hands. While covering hand call, our division has encountered 2 cases of mpox in the emergency department for which the chief complaint was a hand lesion. Because hand surgeons will be called upon to make an initial diagnosis, the purpose of these case reports is to describe the presentation, disease course, treatment, and outcomes of these mpox patients. These patients had both uncontrolled HIV as well as other sexually transmitted disease. Symptoms included painful vesicular hand lesions with ulceration and eventual central necrosis, followed by similar lesions on the face, trunk, and genital area. Diagnosis was made using nucleic acid amplification testing through polymerase chain reaction. The patients were treated with restoration of immunity through control of HIV as well as treatment of all secondary bacterial infections. One patient died in the hospital, and the other survived without any long-term defects.<\/jats:p>","DOI":"10.1177\/15589447231177098","type":"journal-article","created":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T01:43:05Z","timestamp":1686274985000},"page":"NP1-NP5","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Monkeypox Presenting as a Hand Consult in the Emergency Department: Two Case Reports"],"prefix":"10.1177","volume":"18","author":[{"given":"David T.","family":"Mitchell","sequence":"first","affiliation":[{"name":"The University of Texas Health Science Center at Houston, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4840-8326","authenticated-orcid":false,"given":"James A.","family":"Mentz","sequence":"additional","affiliation":[{"name":"The University of Texas Health Science Center at Houston, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuewei","family":"Wu-Fienberg","sequence":"additional","affiliation":[{"name":"The University of Texas Health Science Center at Houston, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wendy","family":"Chen","sequence":"additional","affiliation":[{"name":"The University of Texas Health Science Center at Houston, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew R.","family":"Greives","sequence":"additional","affiliation":[{"name":"The University of Texas Health Science Center at Houston, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik S.","family":"Marques","sequence":"additional","affiliation":[{"name":"The University of Texas Health Science Center at Houston, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,6,8]]},"reference":[{"key":"bibr1-15589447231177098","unstructured":"World Health Organization. Multi-country monkeypox outbreak in non-endemic countries. Published May 21, 2022. Accessed December 15, 2022. https:\/\/www.who.int\/emergencies\/disease-outbreak-news\/item\/2022-DON385."},{"key":"bibr2-15589447231177098","unstructured":"World Health Organization. WHO Director General declares the ongoing monkeypox outbreak a Public Health Emergency of International Concern. Published July 23, 2022. Accessed December 15, 2022. https:\/\/www.who.int\/europe\/news\/item\/23-07-2022-who-director-general-declares-the-ongoing-monkeypox-outbreak-a-public-health-event-of-international-concern."},{"key":"bibr3-15589447231177098","unstructured":"Centers for Disease Control and Prevention. 2022 U.S. map & case count\u2014Mpox\u2014Poxvirus\u2014CDC. Published December 14, 2022. Accessed December 15, 2022. https:\/\/www.cdc.gov\/poxvirus\/monkeypox\/response\/2022\/us-map.html."},{"key":"bibr4-15589447231177098","unstructured":"Centers for Disease Control and Prevention. Signs and symptoms\u2014Mpox\u2014Poxvirus\u2014CDC. Published December 9, 2022. Accessed December 15, 2022. https:\/\/www.cdc.gov\/poxvirus\/monkeypox\/symptoms\/index.html."},{"key":"bibr5-15589447231177098","unstructured":"Centers for Disease Control and Prevention. Mpox cases by age and gender, race\/ethnicity, and symptoms\u2014Mpox\u2014Poxvirus\u2014CDC. Published December 14, 2022. Accessed December 15, 2022. https:\/\/www.cdc.gov\/poxvirus\/monkeypox\/response\/2022\/demographics.html."},{"key":"bibr6-15589447231177098","unstructured":"Philpott D, Hughes CM, Alroy KA, et al. MMWR, epidemiologic and clinical characteristics of monkeypox cases\u2014United States, May 17\u2013July 22, 2022. Published online 2022. Accessed December 15, 2022. https:\/\/www.cdc.gov\/poxvirus\/monkeypox\/index.html."},{"key":"bibr7-15589447231177098","unstructured":"Advisory Board. Monkeypox update: where the outbreak stands now. Published June 14, 2022. Accessed December 15, 2022. https:\/\/www.advisory.com\/daily-briefing\/2022\/06\/14\/monkeypox-update."},{"key":"bibr8-15589447231177098","unstructured":"World Health Organization. Laboratory testing for the monkeypox virus: interim guidance. Published June 27, 2022. Accessed January 11, 2023. https:\/\/www.who.int\/publications\/i\/item\/WHO-MPX-laboratory-2022.1."},{"key":"bibr9-15589447231177098","unstructured":"Centers for Disease Control and Prevention. Clinical recognition\u2014Mpox\u2014Poxvirus\u2014CDC. Published August 23, 2022. Accessed December 16, 2022. https:\/\/www.cdc.gov\/poxvirus\/monkeypox\/clinicians\/clinical-recognition.html."},{"key":"bibr10-15589447231177098","unstructured":"Centers for Disease Control and Prevention. How it spreads\u2014Mpox\u2014Poxvirus\u2014CDC. Published December 8, 2022. Accessed December 16, 2022. https:\/\/www.cdc.gov\/poxvirus\/monkeypox\/if-sick\/transmission.html."},{"key":"bibr11-15589447231177098","unstructured":"Centers for Disease Control and Prevention. Infection control: healthcare settings\u2014Mpox\u2014Poxvirus\u2014CDC. Published October 31, 2022. Accessed December 16, 2022. https:\/\/www.cdc.gov\/poxvirus\/monkeypox\/clinicians\/infection-control-healthcare.html#anchor_1653508909869."},{"key":"bibr12-15589447231177098","doi-asserted-by":"publisher","DOI":"10.3390\/v9120380."}],"container-title":["HAND"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15589447231177098","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/15589447231177098","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15589447231177098","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:28:53Z","timestamp":1777447733000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/15589447231177098"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,8]]},"references-count":12,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["10.1177\/15589447231177098"],"URL":"https:\/\/doi.org\/10.1177\/15589447231177098","relation":{},"ISSN":["1558-9447","1558-9455"],"issn-type":[{"value":"1558-9447","type":"print"},{"value":"1558-9455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,8]]}}}