{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T13:38:44Z","timestamp":1789220324275,"version":"build-2803163510"},"reference-count":18,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2025,5,11]],"date-time":"2025-05-11T00:00:00Z","timestamp":1746921600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Hand (New York, N,Y.)"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>We investigated associations of cannabis and tobacco use with complications after open reduction and internal fixation (ORIF) of wrist fractures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We retrospectively analyzed PearlDiver data from 337\u2009538 patients who underwent ORIF for wrist fractures from 2010 to 2022. We identified 5587 patients with a history of cannabis use disorder (\u201ccannabis group\u201d); 12\u2009806 patients with a history of tobacco use and no history of cannabis use disorder (\u201ctobacco group\u201d), and 310\u2009108 patients with no history of cannabis use disorder or tobacco use (\u201ccontrol group\u201d). We excluded patients with a history of using other illicit drugs. Propensity matching was used to control for age, sex, and comorbidity burden. Demographic characteristics, comorbidity profiles, and medical and surgical complications were compared using chi-squared tests. Complications were assessed within 90 days after surgery. Postoperative outcomes were also stratified by fracture location. Alpha = .05.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Compared with the control group, the cannabis group had a significantly higher incidence of all medical complications and of fracture malunion, nerve injury, and tendon, muscle, or fascia injury. Compared with the tobacco group, the cannabis group had significantly lower incidence of sepsis, pneumonia, deep venous thrombosis, urinary tract infection, nerve injury, and wound dehiscence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Compared with nonusers of cannabis and tobacco, cannabis users had a higher incidence of several medical and surgical complications after ORIF for wrist fractures. These findings will help physicians better anticipate complications in patients who use cannabis or tobacco.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15589447251336399","type":"journal-article","created":{"date-parts":[[2025,5,12]],"date-time":"2025-05-12T02:26:04Z","timestamp":1747016764000},"page":"744-751","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["The Highs and Lows of Fracture Fixation: Complications After Wrist Fracture Fixation for Users of Cannabis, Tobacco, or Neither Substance"],"prefix":"10.1177","volume":"21","author":[{"given":"Arman","family":"Kishan","sequence":"first","affiliation":[{"name":"The Johns Hopkins University School of Medicine, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7332-2141","authenticated-orcid":false,"given":"Victoria E.","family":"Bergstein","sequence":"additional","affiliation":[{"name":"The Johns Hopkins University School of Medicine, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blake","family":"Prieskorn","sequence":"additional","affiliation":[{"name":"West Virginia School of Osteopathic Medicine, Lewisburg, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanley","family":"Zhu","sequence":"additional","affiliation":[{"name":"University of Michigan Medical School, Ann Arbor, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ansh","family":"Kishan","sequence":"additional","affiliation":[{"name":"K. J. Somaiya Institute of Technology, Mumbai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas P.","family":"Cancian","sequence":"additional","affiliation":[{"name":"The Johns Hopkins University School of Medicine, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Visakha","family":"Suresh","sequence":"additional","affiliation":[{"name":"The Johns Hopkins University School of Medicine, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawel P.","family":"Jankowski","sequence":"additional","affiliation":[{"name":"Hoag Orthopedic Institute, Irvine, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sami H.","family":"Tuffaha","sequence":"additional","affiliation":[{"name":"The Johns Hopkins University School of Medicine, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6564-2707","authenticated-orcid":false,"given":"Dawn M.","family":"LaPorte","sequence":"additional","affiliation":[{"name":"The Johns Hopkins University School of Medicine, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,5,11]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/11782218231172054"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-med-050214-013454"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/add.16016"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.7326\/M23-2811"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-023-01101-w"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2023.07.008"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00590-023-03802-9"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.RVW.21.00184"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2023.04.053"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1302\/1358-992X.2022.12.102"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1177\/15589447231196905"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2023.2403"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1177\/15589447231210948"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.295.6612.1516"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.081040"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.xnsj.2023.100265"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/OI9.0000000000000092"}],"container-title":["HAND"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15589447251336399","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/15589447251336399","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15589447251336399","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:30:07Z","timestamp":1777447807000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/15589447251336399"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,11]]},"references-count":18,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1177\/15589447251336399"],"URL":"https:\/\/doi.org\/10.1177\/15589447251336399","relation":{},"ISSN":["1558-9447","1558-9455"],"issn-type":[{"value":"1558-9447","type":"print"},{"value":"1558-9455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,11]]}}}