{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T12:51:37Z","timestamp":1777553497699,"version":"3.51.4"},"reference-count":28,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Dose-Response"],"published-print":{"date-parts":[[2019,7,1]]},"abstract":"<jats:p>Several investigations have focused on studying the suppressing influence of Salvadora persica (miswak) on oral microbes; however, studies regarding its fungicidal activity versus human aspergillosis-related illness are still scarce. The current research was designed to evaluate the fungicidal action of S persica aquatic root extract in terms of radial growth rate and inhibition zone (IZO) versus 3 pathogenic Aspergillus species, namely, A niger, A flavus, and A fumigatus in vitro. The results revealed that the plant extract (50 and 100 mg\/mL) exhibited a prohibiting influence on the growth of the tested fungal species. The high concentration (100 mg\/mL) of the plant extract was efficient in prohibiting the growing rate of the tested Aspergillus species after 6 days exposure period. Aspergillus niger and A flavus showed the largest inhibition ratios (60% and 54.4%, respectively) and IZO (33.00 \u00b1 0.05 mm and 25.50 \u00b1 0.18 mm, respectively) versus the control counterparts. Aspergillus fumigatus showed the minimum inhibition ratio (39%) and IZO (20.31 \u00b1 0.05). The present data showed that the extract of S persica possesses potential fungicidal influence versus the tested pathogenic Aspergillus species and this may support the utilization of this extract as a promising antifungal agent versus aspergillosis.<\/jats:p>","DOI":"10.1177\/1559325819876218","type":"journal-article","created":{"date-parts":[[2019,9,26]],"date-time":"2019-09-26T20:25:59Z","timestamp":1569529559000},"page":"155932581987621","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Fungicidal Impact of\n                    <i>Salvadora Persica<\/i>\n                    L. (Miswak) Extract on Growth of Foodborne Pathogens,\n                    <i>Aspergillus<\/i>\n                    Species"],"prefix":"10.1177","volume":"17","author":[{"given":"Amna Ali","family":"Saddiq","sequence":"first","affiliation":[{"name":"Faculty of Science, Department of Biology, University of Jeddah, Jeddah, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monagi H.","family":"Alkinani","sequence":"additional","affiliation":[{"name":"College of computer Science and Engineering, Department of computer Science and Artificial Intelligence, University of Jeddah, Jeddah, Saudi 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