{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:27:27Z","timestamp":1792290447464,"version":"4.4.0"},"reference-count":28,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Dose-Response"],"published-print":{"date-parts":[[2021,1,1]]},"abstract":"<jats:p>Introduction. Intracranial epidermoid cysts are the most frequent congenital intracranial lesion. They rare and benign tumors that can present in different clinical situations depending on location and extension of the disease. Diagnosis is obtained with radiological imaging with RM and non-enhanced TC as elective investigating methods. Elective treatment is surgery, based on total\/subtotal excision sparring healthy neurovascular structures, considering the benign nature of this lesion. Case Report. In this study we present the case of a 79-year-old woman affected by recidivist epidermal cyst of the posterior fossa. Clinical presentation was characterized by positional subjective vertigo, intense headache localized in the right part of the head increased by Valsalva maneuver and retroarticular subcutaneous swelling. Radiological investigation found a giant epidemoid cyst of the posterior fossa (8,4 x 4,8 x 5,8 cm), treated with surgery. In the postoperative, the patient was fine and no neurological deficit has been encounterd. REVIEW. In this study, we present a review of the literature regarding giant epidermoid cysts of posterior fossa. Only 11 cases were reported before ours, which actually is one of the largest ever described.<\/jats:p>","DOI":"10.1177\/15593258211002061","type":"journal-article","created":{"date-parts":[[2021,3,24]],"date-time":"2021-03-24T06:10:02Z","timestamp":1616566202000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":25,"title":["Giant Epidermoid Cyst of Posterior Fossa\u2014Our Experience and Literature Review"],"prefix":"10.1177","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5295-5077","authenticated-orcid":false,"given":"Giacomo","family":"Spinato","sequence":"first","affiliation":[{"name":"Department of Neurosciences, Section of Otolaryngology and Regional Centre for Head and Neck Cancer, University of Padova, Treviso, Italy"},{"name":"Department of Surgery, Oncology and Gastroenterology, Section of Oncology and Immunology, University of Padova, Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piergiorgio","family":"Gaudioso","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Section of Otolaryngology and Regional Centre for Head and Neck Cancer, University of Padova, Treviso, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Falcioni","sequence":"additional","affiliation":[{"name":"Department of Head and Neck, University Hospital of Parma, Parma, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Cristina Da","family":"Mosto","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Section of Otolaryngology and Regional Centre for Head and Neck Cancer, University of Padova, Treviso, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Cocuzza","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences and Advanced Technologies \u201cGF Ingrassia\u201d, ENT Section; University of Catania, Catania, Sicily, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonino","family":"Maniaci","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences and Advanced Technologies \u201cGF Ingrassia\u201d, ENT Section; University of Catania, Catania, Sicily, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristoforo","family":"Fabbris","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Section of Otolaryngology and Regional Centre for Head and Neck Cancer, University of Padova, Treviso, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doriano","family":"Politi","sequence":"additional","affiliation":[{"name":"Functional Department of Head and Neck, ENT Unit, ULSS3, Venice-Mestre Hospital, Venice, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiziana","family":"Volo","sequence":"additional","affiliation":[{"name":"Functional Department of Head and Neck, ENT Unit, ULSS3, Venice-Mestre Hospital, Venice, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuele","family":"Ferri","sequence":"additional","affiliation":[{"name":"ENT Unit, ULSS 6, Monselice Hospital, Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Cristalli","sequence":"additional","affiliation":[{"name":"ENT Unit, ULSS 6, Monselice Hospital, Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9102-4176","authenticated-orcid":false,"given":"Lorenzo","family":"Mannelli","sequence":"additional","affiliation":[{"name":"IRCCS SDN, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Salvatore","sequence":"additional","affiliation":[{"name":"IRCCS SDN, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo Boscolo","family":"Rizzo","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Section of Otolaryngology and Regional Centre for Head and Neck Cancer, University of Padova, Treviso, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele","family":"Frezza","sequence":"additional","affiliation":[{"name":"Otosurgery Unit, ULSS2, Treviso Hospital, Treviso, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,3,24]]},"reference":[{"key":"bibr1-15593258211002061","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-016-2813-5"},{"key":"bibr2-15593258211002061","doi-asserted-by":"publisher","DOI":"10.3109\/02688697.2015.1125445"},{"key":"bibr3-15593258211002061","doi-asserted-by":"crossref","unstructured":"McLendon RE, Rosenblum MK, Bigner DD.\n                      Russell and Rubinstein\u2019s Pathology of\u00a0Tumors of the Nervous System\n                      7Ed\n                      . 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